Evidence map›Paper›PMID 41096825›Full record

ArticleInternational journal of molecular sciences2025

Sebastián Araneda-Rojas, Christian Castillo, Ana Liempi, Alejandro Fernández-Moya, Jesús Guerrero-Muñoz, Sebastián Alfaro, Christian Gallardo, Rocío Arregui, Anilei Hoare, Maria Alejandra Gleisner and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sebastián Araneda-RojasInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0009-0008-0433-0791
Christian CastilloInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0001-8710-6745
Ana LiempiInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0003-3200-9811
Alejandro Fernández-MoyaInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0002-6039-8239
Jesús Guerrero-MuñozInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Sebastián AlfaroInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Christian GallardoInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0009-0005-9468-3213
Rocío ArreguiInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Anilei HoareLaboratory of Oral Microbiota Ecology, Faculty of Dentistry, Universidad Andres Bello, Santiago 8370133, Chile.ORCID 0000-0002-1617-6401
Maria Alejandra GleisnerInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Marcela HernándezDepartamento de Patología y Medicina Oral y Laboratorio de Biología Periodontal, Facultad de Odontología, Universidad de Chile, Santiago 8380544, Chile.ORCID 0000-0001-8289-7314
Ulrike KemmerlingInstituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.ORCID 0000-0002-0201-1665

Funding

Agencia Nacional de Investigación y Desarrollo 11220310Agencia Nacional de Investigación y Desarrollo 1200098Agencia Nacional de Investigación y Desarrollo 1220105
6 · The paper itself

Abstract

Periodontitis has been associated with adverse pregnancy outcomes, but the effect of oral pathogens on placental tissue and local immunity remains unclear. In this study, we investigated the response of human placental explants (HPEs) to lysates of

Indexed as

InflammationNF-kappa BPlacentaPorphyromonas gingivalisToll-Like Receptor 2Toll-Like Receptor 4CytokinesFemaleHumansPeriodontitisPregnancySignal TransductionCytokinesNF-kappa BTLR2 protein, humanTLR4 protein, humanToll-Like Receptor 2Toll-Like Receptor 4cytokinesNFkB signalingperiodontitisplacentaPorphyromonas gingivalis

Identifiers

PMID41096825
PMCPMC12524479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.