Evidence map›Paper›PMID 41096752›Full record

ArticleInternational journal of molecular sciences2025

Nanostructured Dual-Delivery System with Antioxidant and Synergistic Approach for Targeted Dermal Treatment.

Lucia Dzurická, Julie Hoová, Barbora Dribňáková, Petra Skoumalová, Paola Rappelli, Ivana Márová

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucia DzurickáDepartment of Food Science and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic.ORCID 0000-0003-2682-1897
Julie HoováDepartment of Food Science and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic.
Barbora DribňákováDepartment of Food Science and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic.ORCID 0009-0004-5363-0919
Petra SkoumalováDepartment of Food Science and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic.
Paola RappelliDepartment of Biomedical Sciences, Università Degli Studi di Sassari, Viale S. Pietro 43/B, 07100 Sassari, Italy.ORCID 0000-0002-8218-0257
Ivana MárováDepartment of Food Science and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic.ORCID 0000-0002-2095-1837

Funding

Internal Grant Agency of the Brno University of Technology FCH-S-24-8526
6 · The paper itself

Abstract

Biocompatible nanofibrous dressings integrating bioactive compounds with antioxidative and antimicrobial properties offer a promising solution for effective wound healing. In the presented study, we developed a novel dual-delivery system by combining forcespun nanofibres with poly(3-hydroxybutyrate) (PHB)-liposomes to enhance bioavailability and enable targeted release of bioactive agents (eugenol, thymol, curcumin, ampicillin, streptomycin, gentamicin). These agents exhibited notable antioxidant activity (2.27-2.33 mmol TE/g) and synergistic or partially synergistic antimicrobial effects against

Indexed as

AntioxidantsDrug Delivery SystemsNanostructuresAnti-Bacterial AgentsCell LineCell SurvivalDrug SynergismEugenolHaCaT CellsHumansHydroxybutyratesKeratinocytesLiposomesMicrobial Sensitivity TestsNanofibersPolyestersAnti-Bacterial AgentsAntioxidantsEugenolHydroxybutyratesLiposomespoly-beta-hydroxybutyratePolyestersPolyhydroxybutyratesThymolantimicrobial and antioxidant agentsliposomesnanofibresphytochemicalspolyhydroxybutyratesynergismwound healing

Identifiers

PMID41096752
PMCPMC12525100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.