Evidence map›Paper›PMID 41096744›Full record

ArticleInternational journal of molecular sciences2025

CG-Based Stratification of 8-mers Highlights Functional Roles and Phylogenetic Divergence Markers.

Guojun Liu, Hu Meng, Zhenhua Yang, Guoqing Liu, Yongqiang Xing, Ningkun Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guojun LiuSchool of Life Science and Technology, Inner Mongolia University of Science and Technology, Baotou 014020, China.
Hu MengSchool of Life Science and Technology, Inner Mongolia University of Science and Technology, Baotou 014020, China.
Zhenhua YangSchool of Economics and Management, Inner Mongolia University of Science and Technology, Baotou 014020, China.
Guoqing LiuSchool of Life Science and Technology, Inner Mongolia University of Science and Technology, Baotou 014020, China.
Yongqiang XingSchool of Life Science and Technology, Inner Mongolia University of Science and Technology, Baotou 014020, China.
Ningkun XiaoDepartment of Immunochemistry, Institution of Chemical Engineering, Ural Federal University, Yekaterinburg 620075, Russia.

Funding

National Natural Science Foundation of China 62161043National Natural Science Foundation of China 62401300
6 · The paper itself

Abstract

K-mer analysis is a powerful tool for understanding genome structure and evolution. A "k-mer" refers to a short DNA sequence made up of k nucleotides (where k is a specific integer), while an "m-mer" is a similar concept but with a shorter sequence length. The functional mechanisms of CG-containing k-mers, as well as their potential role in evolutionary processes, remain unclear. To explore this issue, we analyzed 8-mers in several species with varying genomic complexities and evolutionary divergences:

Indexed as

Nucleotide MotifsPhylogenyAnimalsBase CompositionBombyxCaenorhabditis elegansCiona intestinalisCpG IslandsEvolution, MolecularHumansSaccharomyces cerevisiaeZebrafishCG dinucleotideinformation-theoretic analysisk-mer distributionsequence evolution

Identifiers

PMID41096744
PMCPMC12525110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.