Evidence map›Paper›PMID 41096704›Full record

ArticleInternational journal of molecular sciences2025

Dermatophyte-Selective Imidazole-Thiosemicarbazides: Potent In Vitro Activity Against

Agata Paneth, Katarzyna Dzitko, Adrian Bekier, Nazar Trotsko, Katarzyna Suśniak, Anita Ciesielska, Piotr Paneth

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Agata PanethChair and Department of Organic Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-8198-7702
Katarzyna DzitkoDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-3265-0409
Adrian BekierDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-4980-1074
Nazar TrotskoChair and Department of Organic Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-8817-7470
Katarzyna SuśniakDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-1360-5901
Anita CiesielskaDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.
Piotr PanethInstitute of Applied Radiation Chemistry, Faculty of Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.ORCID 0000-0002-3091-8387

Funding

Medical Research Agency KPOD.07.07-IW.07-0038/24Medical University of Lublin DS14University of Lodz, Poland statutory funds
6 · The paper itself

Abstract

Dermatophytes are highly infectious pathogenic fungi that colonize keratinized tissues like skin, hair, and nails, causing superficial infections such as tinea capitis, onychomycosis, tinea corporis, and tinea pedis in humans and animals. In immunocompromised patients, they may invade deeper tissues and organs, leading to severe or life-threatening conditions if untreated or inadequately managed. While most infections respond to topical antifungals, some require complex treatment and show resistance to standard therapies. Therefore, novel antifungal agents are needed. We investigated the antidermatophytic activity of imidazole-thiosemicarbazides against

Indexed as

Antifungal AgentsArthrodermataceaeImidazolesMicrosporumTrichophytonCandidaHumansMicrobial Sensitivity TestsMolecular Docking SimulationAntifungal AgentsimidazoleImidazolesantifungal activitydermatophytesdocking studyimidazolethiosemicarbazide

Identifiers

PMID41096704
PMCPMC12525150

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.