Evidence map›Paper›PMID 41096620›Full record

SynthesisInternational journal of molecular sciences2025

Using

Lilla Bonanno, Miriana Caporlingua, Jole Castellano, Angelo Quartarone, Rosella Ciurleo

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Emerging Role of N-Acetylaspartate in Cancer.International journal of molecular sciences · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lilla BonannoIRCCS Centro Neurolesi "Bonino-Pulejo", Via Palermo S.S. 113, Contrada Casazza, 98124 Messina, Italy.ORCID 0000-0002-0282-405X
Miriana CaporlinguaIRCCS Centro Neurolesi "Bonino-Pulejo", Via Palermo S.S. 113, Contrada Casazza, 98124 Messina, Italy.
Jole CastellanoIRCCS Centro Neurolesi "Bonino-Pulejo", Via Palermo S.S. 113, Contrada Casazza, 98124 Messina, Italy.
Angelo QuartaroneIRCCS Centro Neurolesi "Bonino-Pulejo", Via Palermo S.S. 113, Contrada Casazza, 98124 Messina, Italy.
Rosella CiurleoIRCCS Centro Neurolesi "Bonino-Pulejo", Via Palermo S.S. 113, Contrada Casazza, 98124 Messina, Italy.ORCID 0000-0003-0709-5914

Funding

PNRR - MAD 2022 - 12376035
6 · The paper itself

Abstract

Parkinson's Disease (PD) is the fastest-growing neurological disorder, characterized by the degeneration of dopaminergic neurons. Treatments remain symptomatic, and objective biomarkers for therapeutic response are lacking. This review aims to evaluate the potential of Proton Magnetic Resonance Spectroscopy (

Indexed as

Parkinson DiseaseProton Magnetic Resonance SpectroscopyBiomarkersDopamine AgonistsHumansLevodopaNeuroprotective AgentsBiomarkersDopamine AgonistsLevodopaNeuroprotective Agentsbrain metabolitecannabinoidsdopamine agonistslevodopaMAO-B inhibitorsneurochemical biomarkersneuroprotectionParkinson’s diseaseproton magnetic resonance spectroscopytherapeutic efficacy

Identifiers

PMID41096620
PMCPMC12525049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.