ArticleInternational journal of molecular sciences2025
Long Intergenic Non-Coding RNA 00511 (LINC00511) Genetic Variations and Haplotypes in Breast Cancer: A Case-Controlled Study and Bioinformatics Analysis.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Multi-Omics Analysis of the Effects ofInternational journal of molecular sciences · 2026Article
- Totally implantable venous access port implantation in a breast cancer patient with situs inversus totalis: A case report.The Journal of international medical research · 2026Article
- Prediction of lymphocyte-predominant breast cancer using microRNA expression in cytology specimens.Cancer cytopathology · 2026Article
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6 authors.
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Abstract
Long intergenic non-coding RNA 00511 (LINC00511) has been involved in the development of several types of cancer including breast cancer (BC). Several single nucleotide polymorphisms (SNPs) can be found in the genomic regions of long non-coding RNAs (lncRNAs) and are associated with the tumorigenesis of many cancers. The objective of the current study is to assess whether LINC00511 SNPs (rs11657109, rs9906859, rs17780195, rs1558535, and rs4432291) could be related with BC incidence in the Egyptian population. Five SNPs of LINC00511 were analyzed in a case-control study of 267 BC cases and 150 controls. Logistic regression analysis was used to test the association between LINC00511 SNPs and BC incidence. We found that the TT genotype of rs11657109 significantly increased BC incidence (OR: 2.177, 95%CI: 1.260-3.763) and this SNP was associated with high incidence of luminal A BC specifically using different genetic models. Haplotype (A
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