Evidence map›Paper›PMID 41096468›Full record

ArticleAnimals : an open access journal from MDPI2025

Weight Gain and Tenderness in Nelore Cattle: Genetic Association and a Potential Pleiotropic Role of Transcription Factors and Genes.

Elora R P de S Borges, Lucio F M Mota, Lucas L Verardo, Lucia G de Albuquerque, Marcela R Duarte, Geovana C Santos, Alice S Pereira, Lorena M P de Carvalho, Lilia S Carvalho, Emily A R Almeida and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elora R P de S BorgesLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0001-0315-0907
Lucio F M MotaDepartment of Animal Science, School of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0000-0001-9983-1784
Lucas L VerardoLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0000-0003-1173-2509
Lucia G de AlbuquerqueDepartment of Animal Science, School of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0000-0002-2030-7590
Marcela R DuarteLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0000-0001-7077-9660
Geovana C SantosLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0007-3237-8146
Alice S PereiraLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0009-0605-4759
Lorena M P de CarvalhoLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0009-5103-9347
Lilia S CarvalhoLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0009-9559-4668
Emily A R AlmeidaLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0009-0009-8413-8077
Ana F B MagalhãesLaboratory of Animal Breeding, Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rodovia MGT 367, Km 583, n° 5000, Alto da Jacuba, Diamantina 39100-000, MG, Brazil.ORCID 0000-0003-2063-6957

Funding

FAPEMIG APQ 02203-21FAPESP 2009/16118-5FAPESP 2017/10630-2
6 · The paper itself

Abstract

The inclusion of meat quality traits in breeding programs is a promising strategy to improve beef by selecting animals based on both growth and meat quality. This study aimed to estimate genetic parameters for average daily gain (ADG) and Warner-Bratzler shear force (WBSF), as well as to perform genome-wide association studies (GWAS) to identify genomic regions and transcription factor (TF) binding sites associated with both traits in Nelore cattle. Genetic parameters were estimated using a bi-trait Bayesian model, and GWAS identified key SNPs explaining over 1% of variance in genomic estimated breeding values. Candidate genes near these SNPs were annotated, TF binding sites predicted, and gene-TF networks constructed. Genetic estimates indicated moderate heritability for ADG, low heritability for WBSF, and a small negative genetic correlation between traits. Genomic regions contained 116 and 151 candidate genes for ADG and WBSF, respectively, with 35 shared between traits. Functional analyses highlighted

Indexed as

beef cattlegenetic parametersgenomicsGWASmeat quality

Identifiers

PMID41096468
PMCPMC12523860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.