Evidence map›Paper›PMID 41096453›Full record

ArticleAnimals : an open access journal from MDPI2025

Chimeric Fimbrial Multiepitope Antigen Fused to Double-Mutant LT (dmLT) Induces Antibodies That Inhibit Enterotoxigenic

Jinxin He, Hongrui Liu, Yuexin Li, Jiashu Chang, Yayun Yang, Shaopeng Gu

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinxin HeCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Hongrui LiuCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Yuexin LiCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Jiashu ChangCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Yayun YangCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Shaopeng GuCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study focused on utilizing the double-mutant heat-labile toxin (R192G/L211A) (dmLT) as a backbone protein, into which neutralizing epitopes of ETEC (FaeG, FedF, FanC, FasA, and Fim41a) were embedded. A combination of computational modeling and immunogenicity analysis was conducted to evaluate the dmLT

Indexed as

double-mutant heat-labile toxinenterotoxigenic Escherichia colifimbriaemultiepitope fusion antigenvaccine

Identifiers

PMID41096453
PMCPMC12523420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.