Evidence map›Paper›PMID 41096437›Full record

ArticleAnimals : an open access journal from MDPI2025

Effects of Tributyrin on Antioxidant Capacity, Immune Function, and Liver Macrophage Polarization in Weaned Piglets Under LPS Challenge.

Meng Yuan, Shuai Ning, Dongming Yu, Fei Long, Weite Li, Jun Qi, Yaxu Liang, Changming Hong, Yingzhang Tang, Chunxue Liu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Meng YuanCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Shuai NingCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Dongming YuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Fei LongCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Weite LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jun QiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yaxu LiangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Changming HongCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yingzhang TangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Chunxue LiuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Gaiqin WangInstitute of Animal Nutrition and Health Industry, Anyou Biotechnology, Nanjing Agricultural University, Nanjing 210095, China.
Bencheng WuInstitute of Animal Nutrition and Health Industry, Anyou Biotechnology, Nanjing Agricultural University, Nanjing 210095, China.
Xiang ZhongCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-8622-8078

Funding

Jiangsu Agricultural Science and Technology Innovation Fund CX (24)1012the Fundamental Research Funds for the Central Universities KYCXJC2024001
6 · The paper itself

Abstract

Under intensive farming systems and the global ban on antibiotic growth promoters (AGPs), early-weaned piglets exhibit incomplete physiological development, increasing their susceptibility to stress-related liver dysfunction and growth performance impairments. This study first investigated the effects of dietary supplementation with 0.2% tributyrin on the growth performance of 21-day-old weaned piglets over a 28-day period. Subsequently, on the final day, we examined its influence on antioxidant capacity, immune responses, and liver macrophage polarization using a 2 × 2 factorial challenge model, with the factors being diet (basal or tributyrin-supplemented) and immunological challenge (saline or lipopolysaccharide). The experimental results indicated that tributyrin had a significant enhancement on the average daily gain (ADG) of weaned piglets within the 0-14-day period (

Indexed as

antioxidantimmunitylivermacrophage polarizationserumtributyrinweaned piglets

Identifiers

PMID41096437
PMCPMC12523467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.