Evidence map›Paper›PMID 41096433›Full record

ArticleAnimals : an open access journal from MDPI2025

Reproductive Toxicity Assessment of Four Portuguese Plant Hydrolates: Effects on Oocyte Maturation and Sperm Viability.

Sandra Duarte-da-Fonseca Dias, Luís Pinto-de-Andrade, Joana Rolo, Carlos Gaspar, Patrícia Gomes-Ruivo, Ana Sofia Oliveira, Sandra Saraiva Ferreira, Rita Palmeira-de-Oliveira, José Martinez-de-Oliveira, José Carlos Gonçalves and 2 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sandra Duarte-da-Fonseca DiasRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-0123-8400
Luís Pinto-de-AndradeIPCB-ESA-School of Agriculture, Polytechnic University, Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal.ORCID 0000-0002-9206-2350
Joana RoloRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-5291-212X
Carlos GasparRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-0144-2543
Patrícia Gomes-RuivoRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Ana Sofia OliveiraRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-0659-4386
Sandra Saraiva FerreiraDepartment of Mathematics and Centre of Mathematics and Applications, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0002-9209-7772
Rita Palmeira-de-OliveiraRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0001-9311-8355
José Martinez-de-OliveiraRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
José Carlos GonçalvesIPCB-ESA-School of Agriculture, Polytechnic University, Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal.ORCID 0000-0003-3387-4487
Fernanda DelgadoIPCB-ESA-School of Agriculture, Polytechnic University, Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal.ORCID 0000-0003-1238-9386
Ana Palmeira-de-OliveiraRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.

Funding

European regional development fund 33815
6 · The paper itself

Abstract

Extracts of aromatic medicinal plants have been extensively studied regarding their numerous bioactivities. However, despite being highly used by humans, studies on the safety of these extracts for animal use are scarce. In this study, we aim to contribute to the determination of the safety profile of plant extracts by focusing on the reproductive toxicity of hydrolates (a by-product of essential oils production) of four endogenous Portuguese plants-

Indexed as

Cistus ladaniferCupressus lusitanicaHelychrisium italicumoocytereproductive toxicityspermatozoaThymbra capitataviability

Identifiers

PMID41096433
PMCPMC12523543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.