Utilization of Urinary Neopterin Levels for Pregnancy Diagnosis in Mated Giant Pandas.

He Huang, Yuliang Liu, David C Kersey, Zongjin Ye, Rong Hou, Xianbiao Hu, Mingxi Li

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

He HuangChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

Yuliang LiuChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

David C KerseyKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA 91101, USA.

Zongjin YeChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

Rong HouChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

Xianbiao HuChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

Mingxi LiChengdu Research Base of Giant Panda Breeding, The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu 610081, China.

Funding

Chengdu Research Base of Giant Panda Breeding 2024CPB-B14Chengdu Research Base of Giant Panda Breeding 202503KY0007

6 · The paper itself

Abstract

Neopterin is a well-characterized marker of cell-mediated immunity. Here, we used neopterin as a biomarker to identify the cellular immunity status of breeding giant pandas throughout gestation. Urine samples were collected from captive adult female giant pandas that had entered estrus and were either naturally bred and/or artificially inseminated (AI) during the breeding seasons at the Chengdu Research Base of Giant Panda Breeding. This study was divided into two parts. In the first part, we examined the urinary neopterin and progesterone (Pg) profiles during pregnancy in parturient and nonparturient individuals. From the day of mating to the Pg peak, there was no correlation between neopterin and Pg in both parturient individuals (

Indexed as

biomarkergiant pandaneopterinpregnancy

Identifiers

PMID41096392

DOI10.3390/ani15192796

PMCPMC12523346

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.