ArticlePolymers2025
Hyaluronan-Based Hydrogel Hybrid Insulin Carriers-Preformulation Studies.
Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Hyaluronan-Based Hybrid Systems as Growth Factor Carriers in the Treatment of Chronic Wounds.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This paper proposes hybrid hydrogel insulin carriers based on alginate-hyaluronan (ALG/HA) and hydroxypropyl methylcellulose-hyaluronan (HPMC/HA) for topical application. The inclusion of insulin in a modern dressing can help restore metabolic balance and proper cell signaling in diseased tissue. Preformulation studies of the developed preparations were conducted, including analysis of the in vitro pharmaceutical availability of insulin, rotational and oscillatory rheology tests, and texture profile analysis. It was found that the developed insulin formulations provide an acceptable compromise between rheological and textural properties and ease of application, while ensuring prolonged release of the active substance. The results obtained provide a basis for further preclinical and clinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.