Fabrication of Next-Generation Skin Scaffolds: Integrating Human Dermal Extracellular Matrix and Microbiota-Derived Postbiotics via 3D Bioprinting.

Sultan Golpek Aymelek, Billur Sezgin, Ahmet Ceylan, Fadime Kiran

Abstract read

In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Fabrication and Characterization of Electrospun Cardiac Patches Functionalized with Microbiota-Derived Postbiotics and Decellularized Neonatal Porcine Myocardial Extracellular Matrix for Cardiac Repair.Polymers · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sultan Golpek AymelekPharmabiotic Technologies Research Laboratory, Department of Biology, Faculty of Science, Ankara University, 06100 Ankara, Türkiye.ORCID 0000-0002-1309-4371

Billur SezginDepartment of Plastic, Reconstructive and Aesthetic Surgery, Koc University School of Medicine, 34450 Istanbul, Türkiye.

Ahmet CeylanDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ankara University, 06110 Ankara, Türkiye.

Fadime KiranPharmabiotic Technologies Research Laboratory, Department of Biology, Faculty of Science, Ankara University, 06100 Ankara, Türkiye.ORCID 0000-0002-4536-2959

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the development of an advanced three-dimensional (3D) bioprinted skin scaffold integrating sodium alginate (SA), gelatin (Gel), human skin-derived decellularized extracellular matrix (dECM), and microbiota-derived postbiotics. To ensure a biocompatible and functional ECM source, human skin samples collected during elective aesthetic surgical procedures were utilized. Following enzymatic treatment, the dermal layer was carefully separated from the epidermis and subjected to four different decellularization protocols. Among them, Protocol IV emerged as the most suitable, achieving significant DNA removal while maintaining the structural and biochemical integrity of the ECM, as confirmed by Fourier-transform infrared spectroscopy. Building on this optimized dECM-4, microbiota-derived postbiotics from

Indexed as

3D bioprintingchronic woundextracellular matrixpostbioticsskin tissue engineering

Identifiers

PMID41096291

DOI10.3390/polym17192647

PMCPMC12527064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.