ArticlePolymers2025
Enhancing Antimicrobial and Antioxidant Properties of Chitosan-Based Films with 1-Methylimidazolium-Chitosan.
Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Incorporation of imidazolium chitosan derivative yields scaffolds with enhanced antioxidant, antimicrobial and immunomodulatory properties.Regenerative biomaterials · 2026Article
- Comparing the Printability, Biological and Physicochemical Properties of Bio-Based Photo-Crosslinkable Hydrogels.Polymers · 2025Article
- Chemical Modification of Chitosan with Bioactive Molecules: A Sustainable Approach for Advanced Film Development.International journal of molecular sciences · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The design and the synthesis of functional films with enhanced functionality represent a significant step forward in sustainable material development due to their potential applications. In this study, a novel chitosan derivative (CS-MeIm) was synthetized by chemically modifying chitosan (CS) structure with 1-methyl-1H-imidazole (MeIm), a heterocyclic compound known for its biological properties. This functionalization not only enhances the intrinsic capabilities of CS but also provides a strategic platform for advanced material engineering. The modified compound, CS-MeIm, was incorporated at 10 wt% into films based on CS matrix, which was also reinforced with 1 or 5 wt% of chitin nanowhiskers (ChNw), to improve their functionality for its potential applications. The fabrication process was optimized to ensure the homogeneity and the structural integrity of the films, which were extensively evaluated to study their thermal stability, mechanical integrity, and bioactivity. The incorporation of the imidazole ring into the CS backbone provided a marked enhancement in antioxidant capacity from 3 to 15 μmol Trolox/gram of film; and excellent antimicrobial activity against common microbes, particularly against E. coli with an efficacy of 99.999%. The findings reveal that this chemical modification not only raises the intrinsic properties of CS but also introduces a versatile platform for creating biodegradable films with high functionality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.