Evidence map›Paper›PMID 41095902›Full record

ArticleJournal of clinical medicine2025

Effectiveness and Utility of Genetic Testing in Establishing a Diagnosis of Hereditary Transthyretin Amyloidosis.

Akash Singh, John Wyatt, Marie Théaudin, Chafic Karam, David Kasper, Berthold Streubel, Karen Frascello, Antoine Bondue

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akash SinghAlnylam Pharmaceuticals, London SL6 1DA, UK.ORCID 0000-0002-5513-8352
John WyattAlnylam Pharmaceuticals, Cambridge, MA 02142, USA.
Marie ThéaudinService of Neurology, Neurosciences Department, Lausanne University Hospital (CHUV), University of Lausanne, 1011 Lausanne, Switzerland.ORCID 0000-0002-3026-3595
Chafic KaramDepartment of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-3868-2994
David KasperARCHIMED Life Science GmbH (ARCHIMEDlife), 1110 Vienna, Austria.ORCID 0009-0009-6167-4512
Berthold StreubelClinical Institute of Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Karen FrascelloAlnylam Pharmaceuticals, Cambridge, MA 02142, USA.
Antoine BondueDepartment of Cardiology, Hôpital Universitaire de Bruxelles, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium.

Funding

Alnylam Pharmaceuticals (United States) N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyloidosisATTRvgenetic testingtransthyretinTTR

Identifiers

PMID41095902
PMCPMC12524576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.