ReviewDiagnostics (Basel, Switzerland)2025
Boerhaave Syndrome-Narrative Review.
Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Diagnostic Approach and Therapeutic Management of Spontaneous Esophageal Perforation (Boerhaave's Syndrome): A Systematic Review and Individual Patient-Level Pooled Analysis.Journal of clinical medicine · 2026Review
- Endoscopic closure of cough-induced esophageal rupture during endoscopic submucosal dissection using the reopenable clip-over-the-line method.Endoscopy · 2026Article
- Stepwise endoscopic and surgical management of spontaneous esophageal rupture with severe mediastinal contamination: A case report.Experimental and therapeutic medicine · 2026Article
- Boerhaave Syndrome Caused by Pancreatitis-Induced Gastric Outlet Obstruction: A Case Report.Cureus · 2026Article
- Outcomes after esophageal perforation: A tertiary referral center series.Surgery today · 2026Article
- Article
- Boerhaave Syndrome With Concomitant Duodenal Perforation: A Rare Case Complicated by Mediastinitis and Empyema.Cureus · 2026Article
- Esophageal Perforation in Zollinger-Ellison Syndrome: A Scoping Review of Management and Outcomes.JGH open : an open access journal of gastroenterology and hepatology · 2026Review
- Case Report: Two-stage surgical management of spontaneous oesophageal rupture with extensive necrosis.Frontiers in medicine · 2026Article
- Diagnosis of esophageal pleural fistula via metagenomic next-generation sequencing of pleural effusion: a case report.BMC infectious diseases · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Boerhaave syndrome (BS) and subsequent septic mediastinitis represent a complex cascade of events from esophageal perforation to septic shock. The pathophysiology involves chemical injury, polymicrobial contamination, cytokine storm, endothelial dysfunction, coagulation disorders, and ultimately multiple organ failure. Understanding these mechanisms is crucial for proper therapeutic management that can interrupt this lethal sequence. Due to the complexity of this condition, it is almost impossible to develop a feasible treatment protocol for every situation. The article, through a literature review, evaluates the pathophysiological mechanisms, the consequences of spontaneous esophageal rupture, as well as the therapeutic techniques available for these situations. These elements are the basis of the management of spontaneous esophageal rupture, which involves adapting and customizing the treatment for each patient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.