Evidence map›Paper›PMID 41095644›Full record

ReviewDiagnostics (Basel, Switzerland)2025

Next-Generation Sequencing: A Review of Its Transformative Impact on Cancer Diagnosis, Treatment, and Resistance Management.

Alexandru Isaic, Nadica Motofelea, Teodora Hoinoiu, Alexandru Catalin Motofelea, Ioan Cristian Leancu, Emanuela Stan, Simona R Gheorghe, Alina Gabriela Dutu, Andreea Crintea

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  12. Review
  13. Pandora's Box of AML: HowBiomedicines · 2025
    Review
  14. Review: Detection of Cancer Biomarkers from a Clinical Perspective.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandru IsaicDepartment of General Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0009-0007-4630-3727
Nadica MotofeleaDepartment of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0009-0007-7597-823X
Teodora HoinoiuDepartment of Clinical Practical Skills, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-7753-7621
Alexandru Catalin MotofeleaCentre for Molecular Research in Nephrology and Vascular Disease/MOL-NEPHRO-VASC, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-4297-077X
Ioan Cristian LeancuDepartment of Computer and Information Sciences, Discipline Artificial Intelligence, University of Anglia Ruskin, Cambridge CB1 1PT, UK.
Emanuela StanDepartment of Neuroscience, Discipline of Forensic Medicine, Bioethics, Deontology and Medical Law, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0009-0002-2775-813X
Simona R GheorgheDepartment of Molecular Sciences, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.ORCID 0000-0002-1492-6977
Alina Gabriela DutuDepartment of Molecular Sciences, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.
Andreea CrinteaDepartment of Molecular Sciences, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer biomarkerscomprehensive genomic profilingliquid biopsymulti-omicsNext-Generation Sequencingprecision oncologyspatial transcriptomicstargeted therapy

Identifiers

PMID41095644
PMCPMC12523276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.