Evidence map›Paper›PMID 41095520›Full record

ReviewHealthcare (Basel, Switzerland)2025

To Treat or Not to Treat: A Scoping Review of Speech Treatment for Dysarthria in Amyotrophic Lateral Sclerosis (ALS).

Brooke-Mai Whelan, Danielle Aldridge, Jessica Ruhle, Persephone Whitelock, Shana Taubert, Annette Collins, Elaine Kearney, Salma Charania, Robert D Henderson, Sarah J Wallace and 4 more

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Brooke-Mai WhelanSchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-7909-3160
Danielle AldridgeSchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-5057-194X
Jessica RuhleSchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0009-0008-7823-5500
Persephone WhitelockSchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Shana TaubertRoyal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia.
Annette CollinsRoyal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia.
Elaine KearneySchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Salma CharaniaSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD 4701, Australia.ORCID 0000-0003-3559-0461
Robert D HendersonRoyal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia.
Sarah J WallaceSchool of Health and Rehabilitation Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-0600-9343
Claire MitchellPsychology, Communication and Human Neuroscience, School of Health Sciences, Geoffrey Jefferson Brain Research Centre, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-2445-8468
Kaila L StipancicDepartment of Communicative Disorders and Sciences, University at Buffalo, Buffalo, NY 14214, USA.ORCID 0000-0001-5185-563X
Mili Kuruvilla-DugdaleDepartment of Communication Sciences and Disorders, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-7900-2364
Adam P VogelSchool of Health Sciences, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-3505-2631

Funding

University of Queensland, School of Health and Rehabilitation Sciences, New Staff Research Start-Up Fund N/A
6 · The paper itself

Abstract

backgroundSpeech loss is recognised as one of the most devastating outcomes for individuals with ALS, yet active speech intervention is rarely targeted in this population. Clinicians face significant challenges in managing dysarthria associated with ALS due to the rapidly progressive nature of the disease, historical concerns around intensive exercise accelerating decline, and an absence of direction on restorative and compensatory intervention strategies in current clinical care guidelines. This review evaluates the scope and quality of evidence for speech treatments in ALS to identify knowledge gaps and establish research priorities to guide clinical care.

methodsStudies were retrieved from six electronic databases (PubMed, CINAHL, Embase, Cochrane library, Web of Science, and PsycINFO).

resultsFour studies met inclusion criteria. Treatment approaches included: music-based speech therapy; multisubsystem speech rehabilitation program, tongue strengthening and articulation training; and Lee Silverman Voice Treatment-LOUD

conclusionsDespite the prevalence and impact of dysarthria in this population, evidence for speech treatment remains sparse, of generally low quality, and provides limited guidance for clinical practice. The changing perspective on exercise in ALS warrants rigorous investigation of tailored dysarthria interventions for this population that are minimally fatiguing and enhance speech by making use of residual physiologic support.

Indexed as

amyotrophic lateral sclerosisdysarthriamotor neurone diseasespeechtreatment

Identifiers

PMID41095520
PMCPMC12523638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.