Evidence map›Paper›PMID 41095159›Full record

ReviewPlants (Basel, Switzerland)2025

COP9 Signalosome's Role in Plant Defense Mechanisms.

Zihua Lu, Chao Li, Kelin Deng, Cong Han, Zhihui Shan, Shuilian Chen, Hongli Yang, Yuanxiao Yang, Haifeng Chen, Qingnan Hao

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zihua LuOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Chao LiOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Kelin DengOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Cong HanOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Zhihui ShanOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Shuilian ChenOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Hongli YangOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0009-0003-3130-1201
Yuanxiao YangOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Haifeng ChenOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Qingnan HaoOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0002-7505-2919

Funding

Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences CAAS-ASTIP-2022-OCRIHubei Province Technological Innovation Program 2024BBB003
6 · The paper itself

Abstract

The COP9 signalosome (CSN) is a highly conserved eukaryotic protein complex that plays a crucial role in plant growth, development, and stress responses by modulating the ubiquitination pathway. Emerging evidence underscores its significance in plant immunity, where it orchestrates diverse defense mechanisms, including hormone signaling, reactive oxygen species (ROS), homeostasis, and secondary metabolite (SM) biosynthesis. As a key regulator, CSN influences multiple layers of immune responses, such as pattern-triggered immunity (PTI), effector-triggered immunity (ETI), and systemic acquired resistance (SAR). However, the intricate interplay between CSN and immune regulatory networks remains incompletely understood, and a comprehensive model of its mechanistic framework is still lacking. This review systematically consolidates current knowledge on CSN-mediated immune regulation in plant-pathogen interactions and highlights its role in disease resistance.

Indexed as

COP9 signalosomeplant disease resistanceplant immunityplant–pathogen interaction

Identifiers

PMID41095159
PMCPMC12526134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.