Evidence map›Paper›PMID 41094745›Full record

ArticleJournal of feline medicine and surgery2025

Field safety and efficacy study with a cannabidiol/cannabidiol acid-rich hemp paste in cats with osteoarthritic pain.

Liza M Mulder, Jeanine Deterd Oude Weme, Niels R Blees, Joseph J Wakshlag, Daniel Hughes, Ronald Jan Corbee

Abstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Pain and pain management in cats: an ever-evolving field.Journal of feline medicine and surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liza M MulderDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.ORCID 0009-0002-1625-9386
Jeanine Deterd Oude WemeAnicura de Tweede Lijn, Zwolle, The Netherlands.
Niels R BleesDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0003-1115-8121
Joseph J WakshlagElleVet Sciences, South Portland ME, The Netherlands.
Daniel HughesElleVet Sciences, South Portland ME, The Netherlands.
Ronald Jan CorbeeDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesFeline osteoarthritis (OA) is a common, degenerative joint condition that is an important cause of chronic pain in cats. Cannabinoids have shown potential in reducing pain and inflammation in OA, but research in cats is limited. This study aimed to assess the safety and efficacy of a cannabidiol (CBD)/cannabidiol acid (CBDA) paste would in cats with OA. We hypothesised that CBD/CBDA paste would reduce pain scores and would be safe for use without significant adverse effects.MethodsIn this randomised, double-blinded, placebo-controlled crossover study, client-owned cats with OA were assigned to two study groups and received a 6-week course of both CBD/CBDA paste and a placebo. During the initial consultation and following appointments, cats underwent orthopaedic examination pain assessment with the North Carolina State University Translational Research in Pain (TRiP) Feline Musculoskeletal Pain Index scoring system and blood examination. Owners filled in a bi-weekly questionnaire (Dutch Orthopaedic Rating for Feline Osteoarthritis Pain, DORFOP). TRiP and DORFOP scores were analysed using mixed-effects models. Clinical chemistry in week 6 was compared using paired

Indexed as

CannabidiolCat DiseasesOsteoarthritisAnimalsCatsCross-Over StudiesDouble-Blind MethodFemaleMalePain MeasurementCannabidiolcannabidiolCBD pharmacokineticsnutritional supplementsorthopaedicsosteoarthritisPain managementsurgery

Identifiers

PMID41094745
PMCPMC12536179

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.