Evidence map›Paper›PMID 41094741›Full record

ArticleOrthopaedic surgery2025

Effect of Spinal Versus General Anesthetic on 30-Day Outcomes in Patients With Chronic Obstructive Pulmonary Disease Undergoing Hip Arthroplasty for Femoral Neck Fracture.

David R Christian, Mark A Plantz, Manasa Pagadala, Isaac SontagMilobsky, Michael Peabody, Erik B Gerlach, David W Manning

Abstract readComparative Study
In one paragraph

Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David R ChristianDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.
Mark A PlantzDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1837-4639
Manasa PagadalaDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.
Isaac SontagMilobskyDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.ORCID https://orcid.org/0009-0005-8905-9264
Michael PeabodyDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.
Erik B GerlachDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.
David W ManningDepartment of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with chronic obstructive pulmonary disease (COPD) and femoral neck fractures are at high risk for postoperative complications and mortality. One consideration to reduce risk is the type of anesthesia, although this has not been investigated. The purpose of this study was to compare 30-day complications between use of general and spinal anesthetic in patients with COPD and femoral neck fractures who underwent hip arthroplasty.

methodsPatients with COPD treated with hip arthroplasty for femoral neck fractures were identified on the American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) database between January 1, 2015 and December 31, 2020. Demographics, patient variables, and surgical variables were recorded. Patients were divided into cohorts based on general or spinal anesthetic. Propensity score matching was used to match the two groups. Thirty-day outcome measures were compared between groups using chi-squared test. Logistic regression was used to assess for risk factors for 30-day complications.

resultsFive thousand and forty patients with COPD were identified who underwent arthroplasty for femoral neck fracture-3800 with general anesthesia and 1240 patients with spinal anesthesia. The general anesthesia cohort had higher rates of diabetes (18.4% vs. 15.1%, p = 0.007), congestive heart failure (10.7% vs. 6.7%, p < 0.001), and chronic kidney disease requiring dialysis (2.6% vs. 1.5%. p = 0.019). After matching, the general anesthesia cohort had higher rates of mortality (8.4% vs. 5.8%, p = 0.042), nonhome discharge (85.5% vs. 79.2%, p < 0.001), and unplanned intubation (1.9% vs. 0.7%, p = 0.048). Logistic regression identified general anesthesia to be an independent risk factor for 30-day mortality (RR 1.514 [1.022-2.245]), nonhome discharge (1.626 [1.237-2.138]), and unplanned intubation (RR 1.488 [1.012-2.187]).

conclusionsGeneral anesthesia is an independent risk factor for 30-day mortality, nonhome discharge, and unplanned intubation in patients with COPD undergoing arthroplasty procedures for femoral neck fractures. If possible, spinal anesthetic should be considered as it may reduce the risk of complications in this patient population.

Indexed as

Anesthesia, GeneralAnesthesia, SpinalArthroplasty, Replacement, HipFemoral Neck FracturesPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk Factorschronic obstructive pulmonary diseasefemoral neck fracturegeneral anesthesiahip fracturespinal anesthesia

Identifiers

PMID41094741
PMCPMC12685483

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.