Evidence map›Paper›PMID 41094733›Full record

ArticleChemistry, an Asian journal2026

Red-Light Activable Oxovanadium(IV)-Gold Nanoparticles (VO@AuNPs) for Next-Generation Photodynamic Therapy: Design, Photophysics, and Therapeutic Evaluation.

Gobinda Bag, Souma Ghosh, Ushasri Chilakamarthi, Rajkumar Banerjee, Th David Singh, Mithun Roy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry, an Asian journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gobinda BagDepartment of Chemistry, National Institute of Technology, Langol, Imphal West, Manipur, 795004, India.
Souma GhoshDepartment of Oils, Lipid Science &Technology, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India.
Ushasri ChilakamarthiDepartment of Oils, Lipid Science &Technology, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India.
Rajkumar BanerjeeDepartment of Oils, Lipid Science &Technology, CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, 500007, India.ORCID https://orcid.org/0000-0003-2336-6294
Th David SinghDepartment of Chemistry, National Institute of Technology, Langol, Imphal West, Manipur, 795004, India.
Mithun RoyDepartment of Chemistry, National Institute of Technology, Jirania, West Tripura, Agartala, 799046, India.ORCID https://orcid.org/0000-0003-0045-6342

Funding

Board of Research in Nuclear Sciences (BRNS), Mumbai (37(2)/14/18/2017-BRNS)DST (DST/WISE-PDF/LS-174/2023 (G)Indian Council of Medical Research DST/WISE-PDF/LS-174/2023Indian Council of Medical Research R.11.13/42/2021-GIA/HR
6 · The paper itself

Abstract

Oxovanadium(IV) (VO) complexes have demonstrated considerable potential in photodynamic therapy (PDT). In this study, we report for the first time the conjugation of these VO complexes with gold nanoparticles (AuNPs), aiming to red-shift their absorption profile, and improve cellular uptake, solubility, and overall stability. The resulting VO@AuNPs nanoconjugates were extensively characterized by techniques like IR, UV-visible spectroscopy, DLS, PXRD, EDX, XPS, and TEM. The nanoconjugates exhibited excellent solubility and stability in physiological conditions (5% DMSO-PBS, pH 7.4), along with strong binding to serum albumin, suggesting good potential for systemic delivery. Biological studies revealed effective and selective cytotoxicity against cancer cells under PDT conditions. Cellular uptake assays showed rapid internalization in MDA-MB-231 cells within 2 h. Upon exposure to red light (620-750 nm), the VO@AuNPs displayed enhanced cytotoxic effects, driven by reactive oxygen species (ROS) generation. Specifically, IC

Indexed as

Antineoplastic AgentsCoordination ComplexesGoldLightMetal NanoparticlesPhotochemotherapyPhotosensitizing AgentsVanadatesApoptosisCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorHumansReactive Oxygen SpeciesAntineoplastic AgentsCoordination ComplexesGoldoxovanadium IVPhotosensitizing AgentsReactive Oxygen SpeciesVanadatesApoptosisNext‐generation PDT agentOxovanadium complex‐functionalized gold nanoconjugate (VO@AuNPs)PDT in red lightReactive oxygen species

Identifiers

PMID41094733
PMCPMC13394358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.