Evidence map›Paper›PMID 41094660›Full record

ArticleCost effectiveness and resource allocation : C/E2025

A health economics assessment of self-care with over-the-counter ibuprofen in dysmenorrhoea, migraine and acute rhinosinusitis in the United Kingdom.

Daniela Afonso, Amy Dymond, Isabel Eastwood, William Green, William Laughey, Patricia Aluko, Graham Pennick, Imran Lodhi, Bruce Charlesworth

Abstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniela AfonsoYork Health Economics Consortium (YHEC), University of York, Enterprise House, Innovation Way, York, YO10 5NQ, UK.
Amy DymondYork Health Economics Consortium (YHEC), University of York, Enterprise House, Innovation Way, York, YO10 5NQ, UK. amy.dymond@york.ac.uk.
Isabel EastwoodYork Health Economics Consortium (YHEC), University of York, Enterprise House, Innovation Way, York, YO10 5NQ, UK.
William GreenYork Health Economics Consortium (YHEC), University of York, Enterprise House, Innovation Way, York, YO10 5NQ, UK.
William LaugheyReckitt Healthcare Ltd, Hull, UK.
Patricia AlukoReckitt Healthcare Ltd, Hull, UK.
Graham PennickReckitt Healthcare Ltd, Hull, UK.
Imran LodhiReckitt Healthcare Ltd, Hull, UK.
Bruce CharlesworthReckitt Healthcare Ltd, Hull, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased appropriate use of self-care for minor conditions can reduce the number of healthcare professional appointments and, hence, provide opportunity cost savings to the National Health Service (NHS). The receipt of over-the-counter medications can lead to faster access to treatment, improved health-related quality of life, and fewer education and work days lost.

methodsA model was developed to evaluate the economic impact of a change in the proportion of people using self-care with ibuprofen to manage three conditions (dysmenorrhoea, migraine and acute rhinosinusitis) on preventable healthcare resource use from the perspective of the NHS and Personal Social Services (PSS). The total number of appointments for each condition was estimated from NHS Digital and was based on the number of primary (n = 230,298,091) and secondary (n = 22,839,832) care visits, and the proportion of visits due to each condition (informed by clinical opinion). Work and school days lost were also modelled to estimate the wider indirect costs associated with preventable absences due to delays in receiving treatment. Deterministic sensitivity and scenario analyses were also conducted to estimate the uncertainty associated with the analysis.

resultsThe use of self-care with ibuprofen was increased by 5% in the base case analysis. The results indicate that this increase could prevent 409,243 appointments in the United Kingdom over a one-year time horizon. 882,875 and 117,114 work and school hours lost could also be prevented, respectively. Sensitivity analysis suggests the magnitude of change in self-care, average working hours/pay and appointment waiting times are the main drivers of the model results.

conclusionSelf-care with ibuprofen provides opportunity cost-savings to the NHS and frees up the capacity of healthcare professionals so that they can focus on more severe conditions.

Indexed as

AbsenteeismEconomic evaluationIbuprofenPrimary and secondary careSelfcare

Identifiers

PMID41094660
PMCPMC12523155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.