Evidence map›Paper›PMID 41094649›Full record

ArticleBMC pulmonary medicine2025

Incidence and predictors of postcontrast acute kidney injury following computed tomography angiography and bronchial artery embolization in hemoptysis patients.

Hong-Dou Xu, Liang Yang, Shi-Bing Hu, Yuan Yang

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

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1citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hong-Dou XuDepartment of Interventional Radiology, Gaochun Peoples Hospital affiliated with Jiangsu University, 53 Maoshan Road, Gaochun District,Nanjing , 210029, Jiangsu, China.
Liang YangDepartment of Interventional Radiology, Gaochun Peoples Hospital affiliated with Jiangsu University, 53 Maoshan Road, Gaochun District,Nanjing , 210029, Jiangsu, China.
Shi-Bing HuDepartment of Interventional Radiology, Gaochun Peoples Hospital affiliated with Jiangsu University, 53 Maoshan Road, Gaochun District,Nanjing , 210029, Jiangsu, China.
Yuan YangDepartment of ultrasound, Gaochun Peoples Hospital affiliated with Jiangsu University, 53 Maoshan Road, Gaochun District,Nanjing, 210029, Jiangsu, China. 13813050063@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerforming computed tomography angiography (CTA) before emergency bronchial artery embolization (BAE) plays a critical role in improving the hemoptysis-free survival rate in patients with hemoptysis, but excessive contrast medium may lead to kidney injury deficits within a short duration. In this study, we examined the incidence and predictors of postcontrast acute kidney injury (CA-AKI) when CTA and BAE were performed sequentially to manage hemoptysis.

methodsA retrospective review was conducted on consecutive patients with hemoptysis who underwent emergent CTA and BAE treatment from January 2015 to June 2024. Acute kidney injury(AKI)was assessed at 24 to 72 hours following BAE and was defined as a rise of 26.5 mol/L in serum creatinine from baseline or “1.5-fold” increase in serum creatinine. A Cox proportional hazards regression model was used to identify predictors of postcontrast acute kidney injury.

resultsThe final analysis included 171 patients (mean ± SD age 65.9 ± 11.8 years; 109 females). Postcontrast acute kidney injury occurred in 13/171 (7.6%) patients. None of them required renal replacement therapy. The multivariate analysis results revealed that age over 75 years (HR 3.84(95% CI 1.56–5.42; P = 0.001), diabetes mellitus (HR 3.51, 95% CI 1.45–3.65; P = 0.022), chronic kidney disease(HR 4.86, 95% CI 2.29–12.88; P = 0.001), and a glomerular filtration rate < 30 mL/min/1.73 m2 (HR 4.86, 95% CI 2.29–12.88; P = 0.001) were independent risk factors for postcontrast acute kidney injury.

conclusionsThe incidence of postcontrast acute kidney injury after sequential CTA and BAE is increased in patients with poor baseline renal function (glomerular filtration rate<30 mL/min/1.73 m2), especially those over 75 years of age with diabetes mellitus. However, we did not observe irreversible postoperative deterioration of kidney function in the patients. CTA and BAE should not be delayed by advanced age and renal insufficiency in patients with hemoptysis.

Indexed as

Acute Kidney InjuryBronchial ArteriesComputed Tomography AngiographyContrast MediaEmbolization, TherapeuticHemoptysisAgedCreatinineFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsContrast MediaCreatinineAcute kidney injuryBronchial artery embolizationContrastHemoptysis

Identifiers

PMID41094649
PMCPMC12523201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.