Evidence map›Paper›PMID 41094328›Full record

ArticleTheoretical medicine and bioethics2026

Uncertainty tolerance in healthcare: towards a normative conception.

Paul K J Han, Bjørn Hofmann

Abstract read
In one paragraph

Article in Theoretical medicine and bioethics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Threats to neonatologists' professional identity formation: ethical implications of condensing neonatal-perinatal fellowship.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  3. Observational
  4. Article
  5. Uncertainty as a driving force.Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2026
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul K J HanDivision of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health (NIH), 9609 Medical Center Drive, 3E138, Bethesda, MD, 20892, USA. paul.han@nih.gov.ORCID 0000-0003-0165-1940
Bjørn HofmannCentre of Medical Ethics, University of Oslo, Oslo, Norway.

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

This paper critically analyzes the meaning of uncertainty tolerance (UT), a phenomenon of growing interest in healthcare. Medical practitioners, educators, and researchers have increasingly acknowledged the importance of UT for both clinicians and patients, and called for greater attention to improving it. However, we argue that the prevailing conception of UT is an inadequate normative ideal, due to its narrow understanding of uncertainty as exclusively an aversive state entailing negative outcomes, and of tolerance as merely the endurance of these outcomes. We show how this endurance-based, outcomes-focused conception of UT is both theoretically incoherent and practically unhelpful. We make the case for an alternative conception based not on endurance but adaptation, and focused not on outcomes but moral virtues, which we view as instrumental capacities that enable adaptation. We develop a provisional integrative taxonomy of these key virtues, discuss both the promises and challenges of this new adaptation-based, virtue-focused conception of UT, and identify fruitful directions for future work.

Indexed as

Adaptation, PsychologicalDelivery of Health CareHumansMoralsUncertaintyVirtuesFrameworkUncertaintyUncertainty toleranceVirtues

Identifiers

PMID41094328
PMCPMC12648382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.