Evidence map›Paper›PMID 41094219›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Effect of respiratory physiotherapy on symptom severity in clinical laryngopharyngeal reflux disease: A controlled study.

Pavla Horova, Martin Dvoracek, Karol Zelenik, Jaromir Zatloukal, Tomas Rybnikar, Katerina Raisova

Abstract readControlled Clinical Trial
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Comment on: "Effect of respiratory physiotherapy on symptom severity in clinical laryngopharyngeal reflux disease: a controlled study".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Pavla HorovaDepartment of Physiotherapy, Faculty of Physical Culture, Palacký University Olomouc, Olomouc, 779 00, Czech Republic. pavla.horova01@upol.cz.ORCID http://orcid.org/0000-0002-5785-7799
Martin DvoracekDepartment of Physiotherapy, Faculty of Physical Culture, Palacký University Olomouc, Olomouc, 779 00, Czech Republic.ORCID http://orcid.org/0000-0003-0405-1449
Karol ZelenikDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine and University Hospital of Ostrava, Ostrava, 708 52, Czech Republic.ORCID http://orcid.org/0000-0003-1349-9958
Jaromir ZatloukalDepartment of Respiratory Medicine, University Hospital Olomouc, Olomouc, 779 00, Czech Republic.ORCID http://orcid.org/0000-0002-3207-6355
Tomas RybnikarDepartment of Otorhinolaryngology and Head and Neck Surgery, SPEA Olomouc s.r.o, Olomouc, Czech Republic.ORCID http://orcid.org/0000-0001-8803-1431
Katerina RaisovaDepartment of Physiotherapy, Faculty of Physical Culture, Palacký University Olomouc, Olomouc, 779 00, Czech Republic.ORCID http://orcid.org/0000-0003-3097-0852

Funding

Univerzita Palackého v Olomouci IGA_FTK_2020_018 and IGA_FTK_2023_013
6 · The paper itself

Abstract

purposeInspiratory muscle training (IMT) has demonstrated efficacy in improving symptoms and oesophageal sphincter function in patients with gastroesophageal reflux disease (GERD). However, evidence for its use in laryngopharyngeal reflux (LPR), a related but distinct condition, remains limited and inconclusive. We aim to assess the efficacy of an eight-week respiratory physiotherapy program – comprising IMT and diaphragmatic breathing – in reducing symptom severity in patients with clinical LPR.

methodsIn this prospective, controlled clinical study, 37 patients with clinical LPR were allocated into three groups: a control group receiving dietary and pharmacological treatment and intervention groups receiving the same treatment supplemented with respiratory physiotherapy using either Threshold IMT or Airofit. Maximal inspiratory pressure (PImax) was used to evaluate inspiratory muscle strength. Symptom severity was measured using the Reflux Symptom Index (RSI) and Hull Airway Reflux Questionnaire (HARQ) at baseline and after 8 weeks.

resultsBoth experimental groups showed a significant increase in inspiratory muscle strength (36.3% for Airofit, p = 0.005; 38.3% for Threshold IMT, p < 0.001), unlike the control group (p = 0.260). RSI scores decreased significantly in all groups but was more pronounced in the intervention groups compared to the control group (p < 0.05). HARQ scores improved across all groups without any significant between-group difference.

conclusionsStandard care supplemented with respiratory physiotherapy integrating IMT significantly reduced symptom severity in LPR. Both the Threshold IMT and Airofit devices proved effective. These findings support respiratory physiotherapy as a feasible, non-pharmacological therapeutic option in LPR management.

Indexed as

Breathing ExercisesLaryngopharyngeal RefluxRespiratory MusclesRespiratory TherapyAdultFemaleHumansMaleMiddle AgedMuscle StrengthProspective StudiesSeverity of Illness IndexTreatment OutcomeDiaphragmatic breathingHull airway reflux questionnaireInspiratory muscle trainingLaryngopharyngeal reflux diseaseReflux symptom index

Identifiers

PMID41094219
PMCPMC12605449

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.