Evidence map›Paper›PMID 41094217›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Risk factors for postoperative pharyngocutaneous fistula after total laryngectomy.

Marco Lionello, Elisa Laura, Chiara Varago, Guglielmo Ronzani, Antonio Annese, Martina Venturi, Roberta Marangoni, Giuseppe Di Prinzio, Leonardo Franz, Andy Bertolin

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Marco LionelloENT Departement, Otolaryngology Unit, Vittorio Veneto Hospital, Forlanini 71, Vittorio Veneto, Treviso, Italy. marco.lionello@aulss2.veneto.it.ORCID http://orcid.org/0000-0002-2454-9618
Elisa LauraENT Departement, Otolaryngology Unit, Vittorio Veneto Hospital, Forlanini 71, Vittorio Veneto, Treviso, Italy.
Chiara VaragoENT Departement, Otolaryngology Unit, Vittorio Veneto Hospital, Forlanini 71, Vittorio Veneto, Treviso, Italy.
Guglielmo RonzaniDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Verona, Verona, Italy.
Antonio AnneseENT Department, Cagliari University Hospital, Cagliari, Italy.
Martina VenturiENT and Audiology Unit, Department of Neurosciences, University Hospital of Ferrara, Ferrara, Italy.
Roberta MarangoniENT Department, Santa Maria della Misericordia Hospital, Rovigo, Italy.
Giuseppe Di PrinzioENT and Audiology Unit, Department of Neurosciences, University Hospital of Ferrara, Ferrara, Italy.
Leonardo FranzDepartment of Neuroscience, Audiology Section, Padova University, Treviso, Italy.
Andy BertolinENT Departement, Otolaryngology Unit, Vittorio Veneto Hospital, Forlanini 71, Vittorio Veneto, Treviso, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present study was to retrospectively analyze the most relevant factors and conditions associated with the development of postoperative pharyngocutaneous fistula (PCF).

methodsThe present study retrospectively reviewed the clinical charts of a cohort of 95 patients who underwent TL at our Institution. The predictive value of demographic, clinical and surgical parameters in terms of postoperative PCF development were evaluated through univariate analysis.

resultsStronger predictive factors for developement of post-laryngectomy PCF were (i) preoperative Albumin levels < 3.5 g/dL, (ii) preoperative Hb < 12.5 g/L; (iii) preoperative BMI < 18.5; (iv) Previous treatments, and in particular RT; (v) longer surgical time. On the other hand, primary TEP was not found to be related to higher PCF rates.

conclusionsA preoperative comprehensive assessment of the patient’s overall nutritional status and improvement of the perioperative nutritional support should be always carried out in order to reduce the incidence of postoperative PCF.

Indexed as

Cutaneous FistulaFistulaLaryngeal NeoplasmsLaryngectomyPharyngeal DiseasesPostoperative ComplicationsAgedBody Mass IndexFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsAlbuminFistulaHemoglobinRadiotherapyTotal laryngectomy

Identifiers

PMID41094217

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