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ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Use of machine learning predictive models in sagittal alignment planning in adolescent idiopathic scoliosis surgery.

John Ngo, Kiran Athreya, Brandon Ehrlich, Lois Sayrs, Tricia Morphew, Steven Halvorson, Afshin Aminian

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

John NgoCommunity Memorial Health, Ventura, California, USA.
Kiran AthreyaChildren's Hospital of Orange County, Orange, USA.
Brandon EhrlichChildren's Hospital of Orange County, Orange, USA.
Lois SayrsChildren's Hospital of Orange County, Orange, USA.
Tricia MorphewChildren's Hospital of Orange County, Orange, USA.
Steven HalvorsonChildren's Hospital of Orange County, Orange, USA.
Afshin AminianChildren's Hospital of Orange County, Orange, USA. aaminian@choc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious research has shown that predictive models can optimize surgical planning. This study investigates whether predictive models can be used to accurately predict compensatory changes in sagittal spinopelvic parameters after all-posterior spinal fusion (PSF) in patients with adolescent idiopathic scoliosis (AIS). STUDY

designRetrospective analysis of medical records was performed to identify pediatric patients with Lenke class 1-4 AIS who underwent PSF with implantation of patient-specific rods (PSR) during the period from July 2018 to December 2020. All included patients (n = 34) were followed for at least two years.

methodsSurgical strategies were simulated on preoperative radiographs to achieve desired thoracic kyphosis (TK) for sagittal planning. Previously validated predictive models were used to predict postoperative lumbar lordosis (LL) and pelvic tilt (PT). Pre-contoured patient specific titanium rods were utilized during corrective surgery. Standard radiographic measurements were obtained preoperatively, along with one and two years postoperatively.

resultsAt 2-year follow-up, in the overall cohort, median TK gain was 9.3° vs. preoperative [IQR: -1.9, 20.5] (p = .003) and 4.9° vs. planned [- 1.6, 10.8] (p < .001). Median differences of postoperative vs. predicted in LL and PT were - 3.8° [IQR: - 10.4, 1.4] (p = .006) and - 0.1° [IQR: - 3.7, 3.3] (p = .555), respectively. At 2-year follow-up in the hypokyphotic subgroup (TK < 20°) (n = 12), median TK gain was 22.4° vs. preoperative [IQR: 15.6, 21.2] (p = .002) and 2.1° vs. planned [IQR: - 2.1, 8.1] (p = .239). Median differences of postoperative vs. predicted in LL and PT were - 3.4 [- 9.7, 0.4] (p = .083) and 0.5 [IQR: - 2.0, 2.7] (p = .262), respectively.

conclusionThe predictive models accurately predicted compensatory changes in the spinopelvic parameters of unfused segments after AIS surgery in the hypokyphotic subset of patients up to two years post op, and up to one year post-operatively in our entire cohort.

Indexed as

Machine LearningScoliosisSpinal FusionAdolescentChildFemaleHumansKyphosisLordosisLumbar VertebraeMaleRetrospective StudiesThoracic VertebraeAdolescent idiopathic scoliosisPredictive modelsSagittal alignmentSagittal balanceThoracic kyphosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.