Evidence map›Paper›PMID 41094076›Full record

ArticleCardiovascular and interventional radiology2025

Safety of Knee Arthroplasty Following Genicular Artery Embolization for Knee Osteoarthritis.

Helen Albrecht, Lucas R Cusumano, Mark Little, Erik N Zeegen, Ahmad Al-Rekabi, Nev Davies, Siddharth A Padia

Abstract readClinical StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helen AlbrechtUniversity of California, Los Angeles, USA.
Lucas R CusumanoSection of Interventional Radiology, David Geffen School of Medicine, University of California Los Angeles, 757 Westwood Plaza, Suite 2125, Los Angeles, CA, 90095, USA.
Mark LittleDepartment of Radiology, Royal Berkshire NHS Foundation Trust, Reading, UK.
Erik N ZeegenDepartment of Orthopaedic Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Ahmad Al-RekabiDepartment of Radiology, Royal Berkshire NHS Foundation Trust, Reading, UK.
Nev DaviesDepartment of Orthopaedic Surgery, Royal Berkshire NHS Foundation Trust, Reading, UK.
Siddharth A PadiaSection of Interventional Radiology, David Geffen School of Medicine, University of California Los Angeles, 757 Westwood Plaza, Suite 2125, Los Angeles, CA, 90095, USA. spadia@mednet.ucla.edu.ORCID http://orcid.org/0000-0002-3975-7479

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConcerns may exist as to potential healing complications after knee arthroplasty (KA) following genicular artery embolization (GAE) for knee osteoarthritis (OA). This study evaluates the adverse events related to KA following GAE. MATERIALS AND

methodsThis IRB-approved multi-institution retrospective study (2019-2024) analyzed 47 patients who underwent 48 KA's following 48 GAEs (out of a total of 300 GAEs).. Post KA records were reviewed for the presence of adverse events.

resultsKA was performed by one of 16 orthopedic surgeons at 10 hospitals. Mean time between GAE and KA was 512 ± 330 days. There were 39/48 (81.2%) TKAs and 9/48 (18.8%) partial KAs. Follow-up time after KA was a mean of 369 (± 350) days. Four (4/48 = 8.3%) AEs were reported including two (2/48 = 4.2%) cases of wound healing issues, a stitch abscess and non-infected fluid discharge at the surgical incision. All AEs resolved. There were no significant differences between mean age (64.3 ± 4.2 vs. 68.7 ± 10.7 years, P = 0.239), BMI (25.4 ± 2.67 vs. 27.9 ± 5.2, P = 0.324), number of arteries treated (2.0 ± 0.8 vs. 1.8 ± 0.7, P = 0.693), and time between GAE and KA (491.8 ± 416.5 vs 513.4 ± 326.6 days, P = 0.787) between groups with and without AEs, respectively.

conclusionAdverse events related to GAE for patients undergoing KA are low. GAE should not be considered a contraindication for future KA and may serve as a bridge in those trying to defer KA to a future date.

Indexed as

Arthroplasty, Replacement, KneeEmbolization, TherapeuticOsteoarthritis, KneePostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedRetrospective StudiesGAEGenicular artery embolizationKAKneeKnee arthroplastyOsteoarthritisPainPartial knee arthroplastyPKATKATotal knee arthroplasty

Identifiers

PMID41094076
PMCPMC12665624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.