Evidence map›Paper›PMID 41094060›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

Infant sensory gating and a developmental cascade to autistic traits and anxiety.

Rebecca F Schwarzlose

Abstract readReview
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rebecca F SchwarzloseDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. schwarzlose@wustl.edu.ORCID 0000-0002-8712-4449

Funding

Neural mechanisms of sensory over-responsivity in children with and without ASDR00HD109454 · NICHD · WASHINGTON UNIVERSITY · PI Rebecca Schwarzlose · 2024 to 2026
$747k
Neural mechanisms of sensory over-responsivity in children with and without ASDK99HD109454 · NICHD · WASHINGTON UNIVERSITY · PI SCHWARZLOSE, REBECCA · 2022 to 2023
$263k
NICHD NIH HHS K99 HD109454NICHD NIH HHS R00 HD109454U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) HD109454
6 · The paper itself

Abstract

Disruptions to the infant sensory environment can have lasting effects on neural response properties and behavior in both humans and animals. Recent work has begun to highlight an additional factor in infant sensory experience: differences in inhibitory signaling and sensory gating. Converging work from human and animal studies has begun to implicate a developmental cascade by which impaired sensory gating during a sensitive period of neonatal neurodevelopment promotes a phenotype of sensory over-responsivity, autistic traits, anxiety, and other psychiatric challenges. In this Review, I propose a model for this developmental cascade and highlight how differences in infant sensory responsivity represent an important intermediate phenotype for research, screening, and supportive intervention.

Indexed as

AnxietyAutistic DisorderChild DevelopmentSensory GatingAnimalsHumansInfant

Identifiers

PMID41094060
PMCPMC12618620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.