Evidence map›Paper›PMID 41093964›Full record

ArticleScientific reports2025

Privacy preserving skin cancer diagnosis through federated deep learning and explainable AI.

Naila Sammar Naz, Muhammad Hassaan Mehmood, Fahad Ahmed, Munir Ahmad, Ateeq Ur Rehman, Waleed M Ismael, Khan Muhammad Adnan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naila Sammar NazSchool of Computer Science, National College of Business Administration and Economics, Lahore, 54000, Pakistan.
Muhammad Hassaan MehmoodSchool of Computer Science, National College of Business Administration and Economics, Lahore, 54000, Pakistan.
Fahad AhmedSchool of Computer Science, National College of Business Administration and Economics, Lahore, 54000, Pakistan.
Munir AhmadSchool of Computer Science, National College of Business Administration and Economics, Lahore, 54000, Pakistan.
Ateeq Ur RehmanComputer Science and Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Waleed M IsmaelDepartment of Information Technology, Faculty of Engineering, Azal University for Human Development, Sanaa, Yemen. Waleed.m@auhd.edu.ye.
Khan Muhammad AdnanDepartment of Software, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam-si, 13557, Republic of Korea. adnan@gachon.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The classification of human skin disorders, particularly benign and malignant skin cancer, is thoroughly examined in this study with a focus on protecting data privacy. Traditional visual diagnosis of skin disorders is often subjective and complicated by the varying colors, textures, and shapes of lesions. To address these challenges, we propose a privacy-preserving and explainable deep learning (DL) architecture that leverages secure federated learning (FL) on distributed medical data sources without exposing private patient information, ensuring compliance with data protection regulations. Real-world decentralized scenarios are simulated by dividing a skin image dataset into two classes and distributing it among three clients. The Federated Averaging (FedAvg) method is employed to train the VGG19 model-a well-established convolutional neural network (CNN)-over 25 federated communication rounds, after pretraining on ImageNet and fine-tuning for binary classification. To enhance robustness and diversity, dermatology datasets, such as Kaggle, are often used in similar studies for performance evaluation. Additionally, explainable AI (XAI) techniques, such as Gradient-weighted Class Activation Mapping (Grad-CAM), are incorporated to improve transparency and assist clinicians in visualizing and interpreting the model's decision-making process. Experimental results demonstrate that the federated approach maintains data privacy while achieving high classification performance. This work highlights the potential of combining explainability and FL to develop reliable and privacy-conscious AI solutions for dermatological diagnosis.

Indexed as

Deep LearningPrivacySkin NeoplasmsHumansNeural Networks, ComputerFederated learningGrad-CAMSecure deep transfer learningSkin cancer predictionVGG19

Identifiers

PMID41093964
PMCPMC12528741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.