ArticleScientific reports2025
Privacy preserving skin cancer diagnosis through federated deep learning and explainable AI.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Explainable and secure federated learning for privacy-enhancing skin cancer classification using a lightweight multi-scale CNN.Scientific reports · 2026Article
- A hybrid CNN-XLSTM-GRU deep learning model with autoencoder-based feature selection for hypothyroidism diagnosis.PloS one · 2026Article
- Federated learning for privacy-preserving skin cancer classification using deep neural networks.Frontiers in oncology · 2026Article
- Scalable HMO-CNN-SVM Framework for Skin Lesion Classification: A Metaheuristic-Driven Approach With Parallelizable Optimization for Cluster Deployment.Biomedical engineering and computational biology · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The classification of human skin disorders, particularly benign and malignant skin cancer, is thoroughly examined in this study with a focus on protecting data privacy. Traditional visual diagnosis of skin disorders is often subjective and complicated by the varying colors, textures, and shapes of lesions. To address these challenges, we propose a privacy-preserving and explainable deep learning (DL) architecture that leverages secure federated learning (FL) on distributed medical data sources without exposing private patient information, ensuring compliance with data protection regulations. Real-world decentralized scenarios are simulated by dividing a skin image dataset into two classes and distributing it among three clients. The Federated Averaging (FedAvg) method is employed to train the VGG19 model-a well-established convolutional neural network (CNN)-over 25 federated communication rounds, after pretraining on ImageNet and fine-tuning for binary classification. To enhance robustness and diversity, dermatology datasets, such as Kaggle, are often used in similar studies for performance evaluation. Additionally, explainable AI (XAI) techniques, such as Gradient-weighted Class Activation Mapping (Grad-CAM), are incorporated to improve transparency and assist clinicians in visualizing and interpreting the model's decision-making process. Experimental results demonstrate that the federated approach maintains data privacy while achieving high classification performance. This work highlights the potential of combining explainability and FL to develop reliable and privacy-conscious AI solutions for dermatological diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.