Evidence map›Paper›PMID 41093836›Full record

ReviewBone research2025

Intelligent microstructure materials for diagnosis and treatment of osteoarthritis: progress and AI-enpowered future.

Weijin Gao, Jiahui Zhong, Xinyi Liu, Dan Bai, Mengjie Wu

Abstract readReview
In one paragraph

Review in Bone research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weijin Gao *Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Hangzhou, China.
Jiahui Zhong *Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Hangzhou, China.
Xinyi LiuStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Hangzhou, China.
Dan BaiPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Mengjie WuStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Hangzhou, China. wumengjie@zju.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81970956National Natural Science Foundation of China (National Science Foundation of China) 82270995National Natural Science Foundation of China (National Science Foundation of China) 82470998
6 · The paper itself

Abstract

Osteoarthritis (OA) is a widespread joint disorder that has emerged as a significant global healthcare challenge. Over the past decade, advancements in material science and medicine have transformed the development of functional materials aimed at addressing the complex issues associated with the diagnosis and treatment of OA. This review synthesizes the latest advancements in various types of intelligent micro-structured materials and their design principles. By examining the exceptional structural characteristics of materials with unique properties such as tailored attributes, controllability, biocompatibility, and bioactivity, we emphasize the design of composite materials for precise and early intervention in OA. This is achieved through advanced imaging techniques and machine learning-based analysis, alongside the customization of micro-structured material properties to align with the biological and mechanical requirements of specific joint tissues. This review offers an in-depth analysis of the transformative potential of advanced technologies and artificial intelligence (AI) in the development of innovative solutions for OA diagnosis and therapy. It aims to inform future research and inspire the creation of next-generation smart materials with unprecedented performance, thereby enhancing our capabilities in the prevention and treatment of OA.

Indexed as

Artificial IntelligenceBiocompatible MaterialsOsteoarthritisHumansMachine LearningBiocompatible Materials

Identifiers

PMID41093836
PMCPMC12528451

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.