Evidence map›Paper›PMID 41093653›Full record

ArticleJournal of medicinal chemistry2025

Re/

Chiyi Xiong, Boping Jing, Qizhen Cao, Junjie Li, Merve Alpay, Haiyan Chen, Wai-Kin Chan, Huamin Wang, Amir M Gholizadeh, Diana S-L Chow and 1 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chiyi XiongDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Boping JingDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Qizhen CaoDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Junjie LiDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Merve AlpayDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Haiyan ChenDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Wai-Kin ChanDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, 1400 Pressler St., Pickens Towwer, Houston, Texas 77030, United States.
Huamin WangDepartment of Anatomical Pathology, 1515 Holcombe Blvd, Houston, Texas 77030, United States.
Amir M GholizadehDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.
Diana S-L ChowDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 4849 Calhoun Road, Houston, Texas 77204, United States.
Chun LiDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1881 East Road, Houston, Texas 77054, United States.ORCID 0000-0002-2376-4703

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Development of irreversible electroporation-based rational combinations to potentiate the activity of cancer immunotherapy against pancreatic ductal adenocarcinomaR01CA258540 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHUN LI, Y. Alan Wang · 2022 to 2026
$2.9M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA258540
6 · The paper itself

Abstract

Phenformin has antitumor effects against pancreatic cancer. We report a phenformin complex with the technetium-99m tricarbonyl [

Indexed as

Antineoplastic AgentsMitochondriaOrganotechnetium CompoundsPancreatic NeoplasmsPhenforminRheniumAnimalsCell Line, TumorCell ProliferationHumansMembrane Potential, MitochondrialMiceMice, NudeTheranostic NanomedicineTomography, Emission-Computed, Single-PhotonXenograft Model Antitumor AssaysAntineoplastic AgentsOrganotechnetium CompoundsPhenforminRhenium

Identifiers

PMID41093653
PMCPMC13688134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.