Evidence map›Paper›PMID 41093602›Full record

ArticleAnnals of laboratory medicine2026

Clinico-hematopathologic and Genetic Characteristics of Korean Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: A Retrospective Single-Center Cohort Study.

Jiyeon Kim, Miyoung Kim, Daehyun Chu, Young-Uk Cho, Sang-Hyun Hwang, Seongsoo Jang, Eul-Ju Seo, Eun-Ji Choi, Han-Seung Park, Jung-Hee Lee and 7 more

Abstract read
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In one paragraph

Article in Annals of laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jiyeon KimDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7209-3707
Miyoung KimDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8903-5044
Daehyun ChuDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9086-8740
Young-Uk ChoDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4403-8989
Sang-Hyun HwangDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3201-5728
Seongsoo JangDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0045-1747
Eul-Ju SeoDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8247-3746
Eun-Ji ChoiDepartment of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9568-8877
Han-Seung ParkDepartment of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3577-0665
Jung-Hee LeeDepartment of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3127-0068
Je-Hwan LeeDepartment of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7060-1675
Dok Hyun YoonDepartment of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8289-3548
Heounjeong GoDepartment of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0412-8709
Chan Sik ParkDepartment of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9783-4498
Kyoo-Hyung LeeDepartment of Hematology-Oncology, Ewha Womans University Medical Center, Mokdong Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2841-0779
Chan-Jeoung ParkDepartment of Laboratory Medicine, Green Cross Laboratories, Yongin, Korea.ORCID https://orcid.org/0000-0003-4396-8348
Seungwoo HwangKorean Bioinformation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.ORCID https://orcid.org/0000-0002-6415-9913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Blastic plasmacytoid dendritic cell neoplasms (BPDCNs) are rare and aggressive hematologic malignancies with poorly defined molecular characteristics. Genetic data for Korean patients with this condition are scarce. We conducted the first network-based analysis of Korean patients with BPDCN, using next-generation sequencing (NGS) alongside clinical, morphological, and cytogenetic evaluations. Methods: We included 14 patients diagnosed with BPDCN between 2004 and 2021. Clinical, morphological, and cytogenetic data were collected. Conventional karyotyping and targeted NGS were performed. Network analysis was used to link gene variants with known BPDCN-associated genes. Results: The median age at diagnosis was 52 yrs; the male:female ratio was 1.8:1. Cutaneous and bone marrow (BM) involvement were observed in 79% and 57% of patients at diagnosis, respectively; 85% of those not lost to follow-up eventually showed BM involvement. Allogeneic hematopoietic stem cell transplantation was associated with longer survival compared with chemotherapy alone ( Conclusions: We present the first network-based analysis of Korean patients with BPDCN, along with conventional genetic assessments, highlighting the potential genetic drivers of BPDCN and facilitating the development of targeted therapies for the disease.

Indexed as

Blastic Plasmacytoid Dendritic Cell NeoplasmAdultAgedAsian PeopleDendritic CellsFemaleHematopoietic Stem Cell TransplantationHigh-Throughput Nucleotide SequencingHumansKaryotypingMaleMiddle AgedRepublic of KoreaRetrospective StudiesYoung AdultBlastic plasmacytoid dendritic cell neoplasmCytogeneticsMolecular geneticsNetwork analysisNext-generation sequencing

Identifiers

PMID41093602
PMCPMC13259938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.