ArticleInternal medicine (Tokyo, Japan)2026
Central Retinal Artery Occlusion Induced by Dupilumab: A Unique Manifestation of Eosinophilic Granulomatosis with Polyangiitis.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Dupilumab is widely used to treat type 2 inflammatory diseases; however, rare adverse events, including eosinophilic granulomatosis with polyangiitis (EGPA), may occur. We report the first case of central retinal artery occlusion (CRAO) as a manifestation of EGPA following dupilumab initiation after switching from mepolizumab in a 64-year-old man with severe asthma. The potential for rare but tragic complications such as CRAO should not be overlooked when using dupilumab, particularly when withdrawing or switching medications that suppress eosinophilic activity. Despite a generally poor visual prognosis, early recognition and multidisciplinary management are essential.
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