Evidence map›Paper›PMID 41093333›Full record

ArticleBMJ open2025

Treatment adherence, social support and coping mechanisms among patients with drug-sensitive tuberculosis: a cross-sectional study in two directly-observed therapy centres in southwest Nigeria.

Rasaq Adisa, Deborah Mafolayomi Durojaye

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Rasaq AdisaDepartment of Clinical Pharmacy and Pharmacy Administration, University of Ibadan Faculty of Pharmacy, Ibadan, Nigeria adisaras73@yahoo.co.uk.ORCID http://orcid.org/0000-0002-0213-2723
Deborah Mafolayomi DurojayeUniversity of Ibadan, Ibadan, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate medication adherence, available social support and types of accessible support among patients with drug-sensitive tuberculosis (DS-TB). Coping mechanism(s) in TB management and associations between accessible support(s) and medication adherence were also explored.

designProspective questionnaire-guided cross-sectional study. SETTINGS: The WHO-certified TB directly observed therapy (DOT) clinic of two tertiary hospitals in Ibadan, southwest Nigeria.

participantsAdult patients with DS-TB attending the TB-DOT clinic of the hospitals. OUTCOME MEASURES: Primary outcomes were level of adherence to TB regimens, available social support and type(s) of accessible support. Secondary outcomes were coping mechanisms in TB management, as well as associations between accessible support(s) and medication adherence.

resultsOverall, 152 (89.4%) had optimal adherence. Available social supports were ranked as family (168; 98.8%) >healthcare providers (166; 97.6%) >government (119; 70.0%) >non-governmental organisation (NGO) (118; 69.4%) >religious affiliations (81; 47.6%) >friends (65; 38.2%) >patient association (3; 1.8%). Emotional (168; 98.8%) and financial (137; 80.6%) supports were mostly accessible from family, while drug support (118; 69.4%) was largely received from NGO. Seeking emotional support from family or friends (159; 93.5%) was the most effective coping mechanism. Medication adherence was higher among patients who received health information (p=0.02) and drug support (p=0.03) from the NGO. There was no difference in medication adherence of patients with or without emotional (p=0.20) and financial support (p=0.53) from family, as well as from friends (p=0.31 and p>0.99, respectively).

conclusionNearly ninety per cent of DS-TB patients had optimal adherence. Family was the most available source of social support for TB management, with one hundred and approximately eighty-two per cent respectively citing emotional and financial support as most accessible from the family. Emotional support from family or friends was the most effective coping mechanism in TB management. There is generally a need for initiation and implementation of an expanded social support system for DS-TB patients as a critical step towards achieving the WHO End-TB strategy milestone target.

Indexed as

Adaptation, PsychologicalAntitubercular AgentsMedication AdherenceSocial SupportTuberculosisAdultCross-Sectional StudiesDirectly Observed TherapyFemaleHumansMaleMiddle AgedNigeriaProspective StudiesSurveys and QuestionnairesYoung AdultAntitubercular AgentsMedication AdherencePublic HospitalsSocial SupportTuberculosis

Identifiers

PMID41093333
PMCPMC12530407

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.