ReviewCurrent opinion in immunology2025
Antiviral responses in peripheral and brain neurons.
Review in Current opinion in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Neurotropic viruses represent a public health challenge due to their ability to cause severe neurological conditions, including meningitis, encephalitis, and paralysis. Although many studies have investigated the immune responses to viral infections in the brain and other nervous system targets, most have focused on the effects of resident cells, such as microglia and astrocytes, and infiltrating immune cells, including neutrophils, monocytes, and T cells. However, emerging evidence has demonstrated that neurons themselves mount antiviral responses that suppress viral replication directly and enhance the inhibitory functions of adjacent glial and infiltrating immune cells. In this review, we discuss the intrinsic and extrinsic antiviral responses of neurons, highlighting mechanisms by which they detect viruses and initiate inhibitory responses to protect the nervous system from viral invasion and injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.