Evidence map›Paper›PMID 41092810›Full record

ReviewPharmacological reviews2025

Recent advances in the pharmacology of voltage-gated ion channels.

Diego Lopez-Mateos, Brandon John Harris, Adriana Hernández-González, Vladimir Yarov-Yarovoy, Heike Wulff

Abstract readReview
In one paragraph

Review in Pharmacological reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Pathophysiology of homocysteine: insights into ion channel dysfunction.Pflugers Archiv : European journal of physiology · 2026
    Review
  7. Targeting NaInternational journal of molecular sciences · 2026
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diego Lopez-MateosDepartment of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California.
Brandon John HarrisDepartment of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California.
Adriana Hernández-GonzálezDepartment of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California.
Vladimir Yarov-YarovoyDepartment of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California; Department of Anesthesiology and Pain Medicine, School of Medicine, University of California Davis, Davis, California. Electronic address: yarovoy@health.ucdavis.edu.
Heike WulffDepartment of Pharmacology, School of Medicine, University of California Davis, Davis, California. Electronic address: hwulff@health.ucdavis.edu.

Funding

UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationU54NS127758 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Pamela J Lein · 2022 to 2026
$17.2M
NINDS NIH HHS U54 NS127758
6 · The paper itself

Abstract

Voltage-gated ion channels (VGICs) are critical regulators of membrane potential, cellular excitability, and calcium signaling in both excitable and nonexcitable tissues and constitute important drug targets for neurological, cardiovascular, and immunological diseases. This review describes recent progress in the pharmacology of voltage-gated Na

Indexed as

Calcium ChannelsPotassium Channels, Voltage-GatedVoltage-Gated Sodium ChannelsAnimalsArtificial IntelligenceDrug DiscoveryHumansCalcium ChannelsPotassium Channels, Voltage-GatedVoltage-Gated Sodium Channels

Identifiers

PMID41092810
PMCPMC13095425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.