Evidence map›Paper›PMID 41092527›Full record

ArticleInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2025

Evaluating the risk of diaphragmatic hernia following left diaphragm resections during cytoreductive surgery for ovarian cancer: a Memorial Sloan Kettering Cancer Center Team Ovary study.

Ryan M Kahn, Sarah Anderson, Effi Yeoshoua, Christina Harlev, Sarah Ehmann, Qin Zhou, Alexia Iasonos, Nadeem R Abu-Rustum, Ahmed Al-Niaimi, Vance Broach and 5 more

Abstract read
In one paragraph

Article in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ryan M KahnMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA.
Sarah AndersonMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA.
Effi YeoshouaMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA.
Christina HarlevMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA.
Sarah EhmannMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA.
Qin ZhouMemorial Sloan Kettering Cancer Center, Department of Epidemiology & Biostatistics, New York, NY, USA.
Alexia IasonosMemorial Sloan Kettering Cancer Center, Department of Epidemiology & Biostatistics, New York, NY, USA.
Nadeem R Abu-RustumMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Ahmed Al-NiaimiMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Vance BroachMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Ginger J GardnerMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Kara C LongMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Yukio SonodaMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Oliver ZivanovicMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA.
Dennis S ChiMemorial Sloan Kettering Cancer Center, Department of Surgery, Gynecology Service, New York, NY, USA; Weill Cornell Medical College, Department of OB/GYN, New York, NY, USA. Electronic address: chid@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveTo determine the incidence rate and risk factors associated with the development of diaphragm hernias following left diaphragm procedures at the time of ovarian cancer cytoreduction.

methodsWe retrospectively reviewed data from patients diagnosed with epithelial ovarian, fallopian tube, or primary peritoneal carcinoma who underwent any timeframe of cytoreductive surgery (primary, interval, secondary, tertiary) at our institution from December 2010 to September 2024. Patients were included if they underwent left diaphragm peritonectomy or resection as part of their cytoreductive surgery. The diagnosis of left diaphragm hernia was made by computed tomography of the chest either as an incidental finding during follow-up surveillance or during work-up for symptomatology. We utilized statistical analysis with descriptive proportions with interquartile ranges.

resultsA total of 267 patients with ovarian cancer underwent a left diaphragm peritonectomy or resection as part of their cytoreductive surgery at our institution and were included in the study. The overall median age was 62 years (interquartile range; 52-70) and body mass index 24.9 kg/m

conclusionsDiaphragmatic hernias occurred most often following the setting of concurrent splenectomy; however, splenectomy was not a statistically significant risk factor. These findings provide meaningful insight into the frequency and clinical context in which this complication may arise, addressing a critical knowledge gap in the surgical management of patients with ovarian cancer who require upper abdominal and thoracic procedures.

Indexed as

Carcinoma, Ovarian EpithelialCytoreduction Surgical ProceduresDiaphragmHernia, DiaphragmaticOvarian NeoplasmsPostoperative ComplicationsAgedFemaleHumansMiddle AgedRetrospective StudiesRisk FactorsConcurrent SplenectomyCytoreductive SurgeryDiaphragmatic HerniaOvarian Cancer

Identifiers

PMID41092527
PMCPMC13463790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.