ArticleJournal of occupational health2025
Carbon fiber-laminated epoxy resin causing chronic occupational dermatosis: presentation with erythroderma and dyschromia-a case report.
Article in Journal of occupational health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Epoxy resins are a common cause of occupational allergic contact dermatitis. Carbon fiber-laminated epoxy resin (CFLER) is a newer material with enhanced mechanical properties, but its health effects remain underreported. A 46-year-old male worker developed erythroderma involving >90% of his body surface and dyschromia after chronic exposure to CFLER in a confined workspace. Skin biopsy demonstrated features of chronic dermatitis, and immunohistochemistry revealed uneven melanocyte distribution. Laboratory studies showed elevated immunoglobulin E levels without internal organ dysfunction. Chest radiography indicated prominent bronchovascular markings without clinical symptoms. Intervention with topical clobetasol and avoidance of CFLER led to gradual resolution of erythroderma and improvement of dyschromia. Unlike previous reports focusing on acute epoxy resin dermatitis, this case highlights chronic skin changes and pigmentary alterations. Chronic exposure to CFLER can lead to melanocyte dysfunction, resulting in hyperpigmentation and hypopigmentation. Prompt identification and management are crucial to prevent severe complications such as high-output cardiac failure. This case emphasizes the importance of protective measures against CFLER exposure to prevent severe occupational dermatological conditions, including erythroderma and dyschromia.
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