ArticleArquivos brasileiros de oftalmologia2025
Intrastromal autologous blood injection for treating corneal hydrops.
Article in Arquivos brasileiros de oftalmologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
purposeTo describe the technique and outcomes of intrastromal autologous blood injection in patients with severe corneal hydrops.
methodsNineteen patients with corneal hydrops underwent intrastromal autologous blood injection. Postoperative assessments included best-corrected visual acuity and time to resolution of corneal edema.
resultsCorneal edema resolved within 1 week in 5 patients, within 1 month in 11, and within 3 months in 3. The mean duration of edema persistence was 37.94 ± 33.05 days (range, 6-124). Corneal thickness decreased from 2.06 ± 0.71-mm preoperatively to 1.34 ± 0.65-mm at day 7, 0.85 ± 0.56-mm at day 30, and 0.57 ± 0.13-mm at day 90 (p<0.001). Descemet's membrane (DM) detachment decreased from 1.01 ± 0.75-mm to 0.44 ± 0.57-mm, 0.24 ± 0.36-mm, and 0.08 ± 0.11-mm on postoperative days 7, 30, and 90, respectively (p<0.001). DM break size decreased from 1.12 ± 1.19-mm to 0.62 ± 0.84-mm at 3 months (p<0.005). Three patients developed hematocornea; no other major complications were observed. At 3 months, mean best-corrected visual acuity improved from 2.37 ± 0.66 to 0.41 ± 0.17 logMAR with hard contact lenses (p<0.001).
conclusionsIntrastromal autolo gous blood injection is an effective treatment for severe corneal hydrops, promoting faster edema resolution and visual improvement with minimal complications.
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