ArticleScience advances2025
Impact of intermittent lead exposure on hominid brain evolution.
Abstract read
In one paragraph
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dentine markers of pre/early postnatal lead exposure links with brain, cognitive, and behavioral outcomes in adolescents.medRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Renaud Joannes-BoyauGeoarchaeology and Archaeometry Research Group, Southern Cross University, Military Road, Lismore, NSW 2480, Australia.ORCID 0000-0002-0452-486X
Janaina Sena de SouzaDepartment of Pediatrics and Cellular & Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3904-7458
Manish AroraDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-3350-4657
Christine AustinDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9966-0492
Kira WestawaySchool of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW 2109, Australia.ORCID 0000-0001-5315-778X
Ian MoffatArchaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide, SA, Australia.ORCID 0000-0002-2171-7145
Wei WangInstitute of Cultural Heritage, Shandong University, Qingdao 266237 China.ORCID 0000-0002-5118-7093
Wei LiaoInstitute of Cultural Heritage, Shandong University, Qingdao 266237 China.ORCID 0009-0000-3511-2684
Yingqi ZhangInstitute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China.ORCID 0000-0001-7783-8336
Justin W AdamsPalaeo-Research Institute, University of Johannesburg, Auckland Park, Johannesburg 2006, South Africa.ORCID 0000-0002-6214-9850
Luca FiorenzaDepartment of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800 Australia.ORCID 0000-0001-7110-3398
Flora DérognatGeoarchaeology and Archaeometry Research Group, Southern Cross University, Military Road, Lismore, NSW 2480, Australia.
Marie-Helene MoncelDépartement Hommes et Environnement, Museum National d'Histoire Naturelle, CNRS 7194, Institut de Paléontologie Humaine, 1 rue René Panhard, 75013 Paris, France.
Gary T SchwartzInstitute of Human Origins, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0003-4428-2102
Marian BaileyGeoarchaeology and Archaeometry Research Group, Southern Cross University, Military Road, Lismore, NSW 2480, Australia.ORCID 0000-0001-9994-3444
Filipe F Dos SantosHospital Sirio-Libanes, Sao Paulo 01308-060, Brazil.ORCID 0000-0003-2335-463X
Gabriela D A GuardiaHospital Sirio-Libanes, Sao Paulo 01308-060, Brazil.ORCID 0000-0002-1789-2768
Rafael L V MercuriHospital Sirio-Libanes, Sao Paulo 01308-060, Brazil.ORCID 0000-0003-0223-3089
Pedro A F GalanteHospital Sirio-Libanes, Sao Paulo 01308-060, Brazil.ORCID 0000-0002-4820-4155
Aline M A MartinsISSCOR - Integrated Space Stem Cell Orbital Research, Sanford Consortium of Regenerative Medicine, UCSD, La Jolla, CA 92093, USA.ORCID 0000-0001-9481-0327
Blake L TsuNGeneBioAI Inc., 9810 Summers Ridge Rd. #100, San Diego, CA 92121, USA.ORCID 0009-0003-4319-3738
Christopher A BarnesNGeneBioAI Inc., 9810 Summers Ridge Rd. #100, San Diego, CA 92121, USA.ORCID 0000-0003-2312-7082
John YatesDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-5267-1672
Luiz Pedro PetroskiPontifícia Universidade Católica do Paraná, School of Medicine and Life Sciences, Graduate Program in Health Sciences (PUCPR/PPGCS), Laboratory of Bioinformatics and Neurogenetics (LaBiN), Curitiba, Paraná 80215-901, Brazil.ORCID 0000-0002-0498-7637
Sandra M Sanchez-SanchezDepartment of Pediatrics and Cellular & Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0009-0008-2374-1967
Jose OviedoDepartment of Pharmacology and Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.ORCID 0009-0007-8248-2208
Roberto H HeraiPontifícia Universidade Católica do Paraná, School of Medicine and Life Sciences, Graduate Program in Health Sciences (PUCPR/PPGCS), Laboratory of Bioinformatics and Neurogenetics (LaBiN), Curitiba, Paraná 80215-901, Brazil.ORCID 0000-0001-9885-2735
Bernardo LemosDepartment of Pharmacology and Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.
Matthew TongeGeoarchaeology and Archaeometry Research Group, Southern Cross University, Military Road, Lismore, NSW 2480, Australia.ORCID 0009-0001-0725-9344
Alysson R MuotriDepartment of Pediatrics and Cellular & Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-0867-2875
Funding
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4MUntargeted Analysis ResourceU2CES026561 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROBERT O · 2015 to 2025
$24.5MThe Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3MUntargeted Analysis ResourceU2CES030859 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARORA, MANISH · 2019 to 2025
$8.2MProteogenetics of Autism Spectrum DisordersR01MH100175 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI MUOTRI, ALYSSON R., YATES III, JOHN R · 2013 to 2025
$7.4MEarly Warning Systems for Childhood and Adult DisordersR35ES030435 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2020 to 2026
$6.7MOrganic-metal mixtures and neurodevelopmentR01ES026033 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora, Robert O Wright · 2016 to 2026
$6.1MNovel markers of exposure and pathways of response to ChromiumR01ES027981 · NIEHS · UNIVERSITY OF ARIZONA · PI LEMOS, BERNARDO · 2018 to 2022
$2.0MIllumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600kNCATS NIH HHS UL1 TR004419NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES026033NIEHS NIH HHS R01 ES027981NIEHS NIH HHS R35 ES030435NIEHS NIH HHS U2C ES026561NIEHS NIH HHS U2C ES030859NIH HHS S10 OD026929NIMH NIH HHS R01 MH100175
Abstract
Gene-environmental interactions shape the evolution of brain architecture and function. Neuro-oncological ventral antigen 1 (
Indexed as
Biological EvolutionBrainHominidaeLeadAnimalsForkhead Transcription FactorsFossilsHumansNerve Tissue ProteinsForkhead Transcription FactorsFOXP2 protein, humanLeadNerve Tissue Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.