ArticleScience advances2025
Developmental alterations in brain network asymmetry in 3- to 9-month infants with congenital sensorineural hearing loss.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Functional Near-Infrared Spectroscopy in Hearing Loss: A Systematic Review of Cortical Responses in Distinct Clinical Populations.Brain sciences · 2026Review
- Predictors of Rehabilitation Outcomes Following Pediatric Cochlear Implantation.Journal of clinical medicine · 2026Review
- Imaging the developing brain with near-infrared spectroscopy in cochlear implanted children.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A narrative review of functional near-infrared spectroscopy (fNIRS) applications in hearing loss, tinnitus and vestibular disorders.Frontiers in neuroscience · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Auditory exposure plays a crucial role in shaping brain development, but little is known about whether and how an initial lack of auditory exposure might disrupt the development of functional network lateralization. We addressed this issue by acquiring functional near-infrared spectroscopy data from infants aged 3 to 9 months with congenital sensorineural hearing loss (SNHL). The SNHL infants showed efficient small-world characteristics within each hemisphere. However, unlike typically developing controls, who showed an age-related leftward lateralization of network efficiencies, SNHL infants did not exhibit the emergence of hemispheric asymmetry. Intriguingly, lateralization of frontal efficiency was preserved in SNHL infants with mild hearing loss but declined significantly with increasing severity of hearing impairment. These findings suggest that even SNHL infants with some residual hearing experience disruption in the development of functional lateralization. This underscores the importance of providing early auditory access to SNHL infants to support robust functional integration during early development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.