Evidence map›Paper›PMID 41091577›Full record

ArticleMolecular biology of the cell2025

Matrix metalloproteinase 2 destabilizes Dally-like protein to restrict extracellular Wingless distribution.

Indrayani Waghmare, Patrick S Page-McCaw, Andrea Page-McCaw

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Indrayani WaghmareDepartment of Biological Sciences, University of Massachusetts Lowell, Lowell, MA 01854.
Patrick S Page-McCawDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.
Andrea Page-McCawDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.

Funding

Integrated Biological Systems Training in OncologyT32CA119925 · NCI · VANDERBILT UNIVERSITY · PI Vivian Gama, William Patrick Tansey · 2008 to 2026
$7.6M
Wnt/Wg Extracellular Ligand Distribution and RegulationR01GM117899 · NIGMS · VANDERBILT UNIVERSITY · PI PAGE-MCCAW, ANDREA · 2016 to 2019
$1.4M
Mechanisms of Tissue RepairR35GM156631 · NIGMS · VANDERBILT UNIVERSITY · PI Andrea Page-McCaw · 2025 to 2026
$846k
Mechanisms of Wg/Wnt regulation by glypican DlpR00GM141414 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI Indrayani Waghmare · 2024 to 2026
$747k
Mechanisms of Wg/Wnt regulation by glypican DlpK99GM141414 · NIGMS · VANDERBILT UNIVERSITY · PI WAGHMARE, INDRAYANI · 2022 to 2023
$221k
NCI NIH HHS T32 CA119925NIGMS NIH HHS K99 GM141414NIGMS NIH HHS R00 GM141414NIGMS NIH HHS R01 GM117899NIGMS NIH HHS R35 GM156631
6 · The paper itself

Abstract

Cell-surface glypicans distribute several extracellular ligands, including the Wnts, which are secreted to function at short and long range in a tissue. The

Indexed as

Drosophila ProteinsGlypicansMatrix Metalloproteinase 2Wnt1 ProteinAnimalsDrosophilaDrosophila melanogasterFemaleOvaryProteoglycansSignal TransductionWnt Signaling Pathwaydlp protein, DrosophilaDrosophila ProteinsGlypicansMatrix Metalloproteinase 2Proteoglycanswg protein, DrosophilaWnt1 Protein

Identifiers

PMID41091577
PMCPMC12636523

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.