Trial reportClinical oral investigations2025
The efficacy of injectable platelet-rich fibrin versus photobiomodulation therapy on palatal wound healing: a randomized, controlled, clinical trial.
Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06744270 (Inonu University Clinical Research Ethics Committee), which is not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Inonu University Clinical Research Ethics Committee
Who cites it
3 citing papers in PubMed.
- Palatal Donor-Site Healing and Patient-Reported Outcome Measures Following Chitosan and Injectable Platelet-Rich Fibrin-Enriched Chitosan Application Compared with Gelatine Sponge: A Three-Arm Randomised Controlled Clinical Trial.Journal of clinical periodontology · 2026Trial
- Comparison of injectable platelet-rich fibrin, titanium platelet-rich fibrin, and 0.8% hyaluronic acid applications versus periodontal dressing alone in wound healing after gingivectomy and gingivoplasty operations: randomized controlled clinical study.Clinical oral investigations · 2026Trial
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to compare the efficacy of photobiomodulation therapy (PBMT) and injectable platelet-rich fibrin (i-PRF) applied to the palatal donor site following harvesting a free gingival graft (FGG), regarding wound healing and postoperative patient morbidity. MATERIALS AND
methodsA total of 36 patients who required FGG were randomly assigned into 3 groups; PBMT (n = 12), i-PRF (n = 12), and control (n = 12). Wound healing was evaluated at the clinic follow-up examinations of the patients at 3, 7, 14, 21, and 30 days postoperatively. Evaluations were made with the palatal early healing index, the hydrogen peroxide foaming test, and measurements of the wound size with Image J program on photographs. Pain severity was measured with a VAS, and analgesia consumption was recorded. Data were analyzed with ANOVA, Kruskal-Wallis, Chi-square, and Friedman tests.
resultsThe total wound surface area on days 3,7,14, and 21 was determined to be significantly greater in the control group than in the test groups. The VAS pain scores on days 3 and 14 were found to be significantly higher in the control group than in the test groups. Analgesia consumption in the control group was higher than in the PBMT group on postoperative day 3. On days 5 and 7, the control group required significantly more analgesia than the i-PRF group.
conclusionThe application of i-PRF and PBMT was seen to accelerate wound healing, and decrease pain levels and the need for analgesia of the patients. Registry: ClinicalTrials.gov, NCT06744270, Registration date: 19 December 2024. CLINICAL RELEVANCE: The shorter time, lower costs and need for less clinical follow-up of i-PRF rendered it more advantageous than PBMT.
Indexed as
Identifiers
41091419What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.