ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
A novel score system for imminent new vertebral fracture risk after vertebral augmentation: the predictive value of lumbar intervertebral disc degeneration.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo assess the predictive value of lumbar intervertebral disc degeneration (IVDD) in determining new vertebral fracture (NVF) after vertebral augmentation (VA) within 2 years for patients with osteoporotic vertebral compression fracture (OVCF) and develop the NVF score system for preoperative prediction of NVF.
methodsPatients with painful OVCF and VA were divided into two groups according to whether NVF occurred within 2 years after VA. Preoperative lumbar magnetic resonance imaging was used to evaluate IVDD depending on Pfirrmann grade. Multivariable regression analysis was used to select independent predictors for imminent NVF. Scores were assigned to each predictor based on the regression coefficient and the NVF score system was established. The predictive performance was assessed by area under the curve (AUC), sensitivity, and specificity for each score cutoff.
resultsA total of 186 patients (71.7 ± 8.5 years; 157 females; 76 NVF) were included. The prevalence of multi-level severe lumbar IVDD in the NVF group was higher than in the group without-NVF (P < 0.001). Age > 76 years (OR = 2.178, 95% Cl = 1.025-4.628, P = 0.043), previous vertebral fracture (OR = 2.719, 95% Cl = 1.350-5.477, P = 0.005), BMD < 50.6 mg/cm
conclusionsAge > 76 years, previous vertebral fracture, BMD < 50.6 mg/cm
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