Evidence map›Paper›PMID 41091174›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Real-world outcomes of scleral-fixated intraocular lens: a multi-surgeon study comparing four-point fixation and flanged intrascleral haptic fixation techniques.

Stanley S J Poh, Shayne S Tan, Andrew S H Tsai, Sin Yee See, Hla Myint Htoon, Daniel S W Ting, Ning Cheung, Edmund Y M Wong, Gavin S W Tan, Shu Yen Lee

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Stanley S J Poh *Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Shayne S Tan *Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Andrew S H TsaiSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Sin Yee SeeYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hla Myint HtoonSingapore Eye Research Institute, Singapore, Singapore.
Daniel S W TingSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Ning CheungSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Edmund Y M WongSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Gavin S W TanSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Shu Yen LeeSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore. shuyen29@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare outcomes between two scleral-fixed intraocular lens (IOL) (SFIOL) techniques: four-point fixation and flanged intrascleral haptic fixation.

methodsThis was a retrospective study conducted between 2018 and 2022 on eyes that underwent SFIOL using either four-point fixation or flanged intrascleral haptic fixation. We compared the visual outcomes and postoperative complications between groups. Subgroup analyses were performed for eyes that underwent pars plana vitrectomy (PPV), flanged intrascleral haptic fixation with versus without PPV, and high myopia versus non-high myopia.

results304 eyes from 294 patients were included with a mean follow-up duration of 702.62 ± 537.9 days. Four-point fixation demonstrated better best corrected VA at 3 months (0.24 ± 0.35 vs. 0.37 ± 0.60 logMAR, p = 0.032), with a higher proportion of eyes achieving VA 0.3 logMAR or better (80.7% vs. 71.0%, p = 0.132). This difference remains significant in the subgroup of eyes that underwent PPV between four-point fixation and flanged intrascleral haptic fixation (0.24 ± 0.35 vs. 0.39 ± 0.64 logMAR respectively, p = 0.024), specifically among non-highly myopic eyes (0.24 ± 0.34 vs. 0.39 ± 0.60 logMAR respectively, p = 0.043). Postoperative IOL-related complications were comparable between the two techniques (all p > 0.05). Among eyes undergoing flanged intrascleral haptic fixation, those with PPV had higher rates of transient postoperative hypotony compared with those without PPV (12.9% vs. 1.5%, p = 0.006).

conclusionFour-point fixation achieved better best corrected VA at 3 months compared with flanged intrascleral haptic fixation, while both techniques demonstrated similar postoperative complication rates.

Indexed as

Lenses, IntraocularLens Implantation, IntraocularRefraction, OcularScleraSuture TechniquesVisual AcuityAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsProsthesis DesignRetrospective StudiesFlanged intrascleral haptic fixationFour-point fixationScleral-fixated intraocular lensYamane fixation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.