ReviewClinical cancer research : an official journal of the American Association for Cancer Research2025
Facts and Hopes for Neoantigen-Enriched TIL.
Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
After decades of development, adoptive transfer of tumor-infiltrating lymphocytes (TIL) or TIL immunotherapy was approved by the U.S. FDA for patients with checkpoint-refractory metastatic melanoma in 2024. Application of the strategy to more common epithelial cancers has depended on the translation of key findings about tumor and T-cell interactions derived from studies of patients with melanoma. Central to that effort has been the identification of neoantigens and neoantigen-reactive TIL. Using laboratory techniques to guide the selection of TIL has mediated modest tumor regression, but new strategies to enrich TIL remain in development in the hopes of improving clinical efficacy in the treatment of solid tumors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.