Evidence map›Paper›PMID 41090727›Full record

ArticleCells2025

A Pleiotropic and Functionally Divergent

Ryota Sugawara, Marcello Scala, Sara Cabet, Carine Abel, Louis Januel, Gaetan Lesca, Laurent Guibaud, Frédérique Le Breton, Hiroshi Ueda, Hidenori Tabata and 2 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ryota SugawaraDepartment of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.
Marcello ScalaDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-2194-7239
Sara CabetPediatric and Fetal Imaging Department, Femme-Mère-Enfant Hospital, Hospices Civils de Lyon, Claude Bernard Lyon 1 University, 69500 Lyon, France.
Carine AbelDepartment of Genetics, Groupement Hospitalier Est, Hospices Civils de Lyon, 69777 Bron, France.
Louis JanuelDepartment of Genetics, Groupement Hospitalier Est, Hospices Civils de Lyon, 69777 Bron, France.
Gaetan LescaPathology and Genetics of Neuron and Muscle, Neuromyogene Institute, CNRS UMR 5261 INSERM U1315, University of Lyon-Université Claude Bernard Lyon 1, 69500 Lyon, France.ORCID 0000-0001-7691-9492
Laurent GuibaudPediatric and Fetal Imaging Department, Femme-Mère-Enfant Hospital, Hospices Civils de Lyon, Claude Bernard Lyon 1 University, 69500 Lyon, France.
Frédérique Le BretonDepartment of Pathology, Hospices Civils de Lyon, 69777 Bron, France.
Hiroshi UedaUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Yanagido, Gifu 501-1193, Japan.
Hidenori TabataDepartment of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.ORCID 0000-0003-3324-5998
Hidenori ItoDepartment of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.ORCID 0000-0002-6527-477X
Koh-Ichi NagataDepartment of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai 480-0392, Japan.ORCID 0000-0002-6827-8434

Funding

Japan Society for the Promotion of Science JP22H03049, JP20K21589
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Organogenesisrac GTP-Binding ProteinsAnimalsChlorocebus aethiopsCOS CellsFemaleHumansMaleMiceMutationNeurodevelopmental DisordersNeuronsPregnancyRAC3 protein, humanRac3 protein, mouserac GTP-Binding Proteinsfetopathyfunctional divergenceneurodevelopmental disorderRAC3small GTPase

Identifiers

PMID41090727
PMCPMC12523998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.