Kuwanon A Targeted YWHAB in Hepatocellular Carcinoma Cells to Inhibit the Raf/MEK/ERK Signaling Pathway.

Jingyang Xu, Hongbo Chang, Yongzhao Wang, Yi Du, Liping Zhong, Hongjuan Cui

Abstract read

In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingyang XuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.

Hongbo ChangState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.

Yongzhao WangState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.

Yi DuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.

Liping ZhongState Key Laboratory of Targeting Oncology, Guangxi Medical University, Nanning 530021, China.

Hongjuan CuiState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.ORCID 0000-0003-1178-1570

Funding

Fundamental Research Funds for the Central Universities SWU-KT22034Fundamental Research Funds for the Central Universities SWU-XDZD22006Natural Science Foundation of Chongqing cstc2020jcyj-msxmX0678Natural Science Foundation of Chongqing cstc2021jcyj-cxtt0005Natural Science Foundation of Chongqing cstc2022ycjh-bgzxm0145Science and Technology Major Project of Guangxi No. AA24011002

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide, and the lung is one of the most frequent metastatic sites for HCC. In this study, we aimed to identify a mild active substance in

Indexed as

Carcinoma, HepatocellularFlavonoidsLiver NeoplasmsMAP Kinase Signaling Systemraf KinasesAnimalsCell Line, TumorCell MovementCell ProliferationFlavonesHumansMiceMice, Inbred BALB CMice, NudeMorusSorafenibFlavonesFlavonoidskuwanon Araf KinasesSorafenibchemosensitivityhepatocellular carcinomaKuwanon AYWHAB

Identifiers

PMID41090717

DOI10.3390/cells14191487

PMCPMC12523843

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.